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Diagnosis and prevention of viral tick-borne encephalitis in Hokkaido

Research Project

Project/Area Number 07456138
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied veterinary science
Research InstitutionHOKKAIDO UNIVERSITY

Principal Investigator

TAKASHIMA Ikuo  Hokkaido Univ., Grad.School of Vet.Med.., Pro., 大学院・獣医学研究科, 教授 (30002083)

Co-Investigator(Kenkyū-buntansha) KARIWA Hiroaki  Hokkaido Univ., Grad.School of Vet.Med., Lecturer., 大学院・獣医学研究科, 講師 (70224714)
Project Period (FY) 1995 – 1997
Project Status Completed (Fiscal Year 1997)
Budget Amount *help
¥8,500,000 (Direct Cost: ¥8,500,000)
Fiscal Year 1997: ¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1996: ¥2,400,000 (Direct Cost: ¥2,400,000)
Fiscal Year 1995: ¥4,000,000 (Direct Cost: ¥4,000,000)
KeywordsViral encephalitis / Tick-borne infection / Arbovirus / Rossian Spring Summer encephalitis
Research Abstract

Epidemiological investigations of tick-borne encephalitis were performed in the endemic foci where the tick-borne encephalitis patient was found and also in the other areas in Hokkaido. Results wre summarized as follows.
1) In 1995, three strains of tick-borne enchephalitis virus were isolated from the blood of the sentinel dogs which were kept in the area where the patient was found.
2) Two strains of tick-borne encephalitis were isolated from 600 individuals of Ixodes ovatus ticks, giving a field infection rate of 0.3% (2/600).
3) Two strains of tick-borne encephalitis virus were isolated from rodents, one from Apodemus speciosus and another from Clethrionomis rufocanus.
4) Virus strains isolated from dogs, ticks and rodents were identifiend as Russian Spring Summer encephalitis type of tick-borne encephalitis virus.
5) Endemic ares of the virus were distributed in 4 districs of southern Hokkaido. These results indicate that tick-borne encephalitis virus is endemic in Hokkaido and maintained by the vector ticks Ixodes ovatus and rodents.

Report

(4 results)
  • 1997 Annual Research Report   Final Research Report Summary
  • 1996 Annual Research Report
  • 1995 Annual Research Report
  • Research Products

    (21 results)

All Other

All Publications (21 results)

  • [Publications] Takashima, I.et al.: "A case of tick-borne encephalitis in Japan and isolation of the virus." J.Clin.Micrlbiol.35. 1943-1947 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Takeda, T.et al.: "Isolation of tick-borne encephalitis virus from Ixodes ovatus (Acari:Ixodidae)in Japan." J.Med.Entomol. (in press). (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Takashima, I.: "Epidemiology of tick-borne encephalitis in Japan." Comp.Immun.Microbiol.Infect.Dis.(in press). (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 高島 郁夫: "ダニ脳炎の疫学" 北獣会誌. 39. 214-219 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 高島 郁夫: "ダニ脳炎の汚染指標動物としてイヌを用いた疫学調査" 獣医畜産新報. 49. 655-659 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 高島 郁夫: "アルボウイルス感染症の疫学" 獣医情報科学雑誌. 37. 17-23 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Takeda, T., Ito, T., Osada, M., Takahashi, K.and Takashima, I.: "Isolation of tick-borne encephalitis virus from Ixodes ovatus (Acari : Ixodidae) in Japan." J.Med.Entomol.(in press). (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Takashima, I.: "Epidemiology of tick-borne encephalitis in Japan." Microbiol.Infect.Dis.Comp.Immuno.(in press). (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Takashima, I., Morita, K., Chiba, M., Hayasaka, D., Sato, T., Takezawa, C., Igarashi, A., Kariwa, H., Yoshimatsu, K., Arikawa, J.and Hashimoto, N.: "A case of tick-borne encephalitis in Japan and isolation of the virus." J.Clin.Microbiol.35. 1943-1947 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Takashima, I.: "Epidemiology of arbovirus infectious symptom. , (in Japanese)." Japan Journal of Veterinary Informatics. 37. 17-23 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Takashima, I.: "Epidemiological survey of tick-borne encephalitis using sentinel dogs as indicator animals. (in Japanese)." Journal of Veterinary Medicine. 49. 655-659 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Takashima, I.: "Epidemiology of tick-borne encephalitis. (in Japanese)." Journal of Hokkaido Veterinary Medical Association. 39. 214-219 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Takashima,I.et al.: "A case of tick-borne encephalitis in Japan and isolation of the virus." J.Clin.Microbiol.35. 1943-1947 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Takeda,T.et al.: "Isolation of tick-borne encephalitis virus from Ixodes ovatus(Acari:Ixodidae)in Japan." J.Ned.Entomol. (in press). (1998)

    • Related Report
      1997 Annual Research Report
  • [Publications] Takashima,I.: "Epidimiology of tick-borne encephalitis in Japan." Comp.Immun.Microbiol.Infect.Dis.(in press). (1998)

    • Related Report
      1997 Annual Research Report
  • [Publications] 高島 郁夫: "ダニ脳炎の疫学" 北獣会誌. 39. 214-219 (1995)

    • Related Report
      1997 Annual Research Report
  • [Publications] 高島 郁夫: "ダニ脳炎の汚染指標動物としてイヌを用いた疫学調査" 獣医畜産新報. 49. 655-659 (1996)

    • Related Report
      1997 Annual Research Report
  • [Publications] 高島 郁夫: "アルボウイルス感染症の疫学" 獣医情報科学雑誌. 37. 17-23 (1996)

    • Related Report
      1997 Annual Research Report
  • [Publications] 高島郁夫: "ダニ脳炎の疫学" 北獣会誌. 39. 214-219 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] 高島郁夫: "ダニ脳炎の汚染指標動物としてイヌを用いた疫学調査" 獣医畜産新報. 49. 655-659 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 高島郁夫: "アルボウイルス感染症の疫学" 獣医情報科学雑誌. 37. 17-23 (1996)

    • Related Report
      1996 Annual Research Report

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Published: 1995-04-01   Modified: 2016-04-21  

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