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A cohort study of two communities with different characteristics on risk factors for osteoporosis

Research Project

Project/Area Number 07457111
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionWakayama Medical College

Principal Investigator

HASHIMOTO Tsutomu  Proffessor, Wakayama Medical College, 医学部, 教授 (70118454)

Co-Investigator(Kenkyū-buntansha) KASAMATSU Takahiro  Profesor, Kobe City College of Nursing, 看護学部, 教授 (20073695)
MORIOKA Seiji  Lecturer, Wakayama Medical College, 医学部, 講師 (70244754)
YOSHIMURA Noriko  Assitant, Wakayama Medical College, 医学部, 助手 (60240355)
Project Period (FY) 1995 – 1997
Project Status Completed (Fiscal Year 1997)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥5,200,000)
Fiscal Year 1997: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1996: ¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 1995: ¥3,100,000 (Direct Cost: ¥3,100,000)
Keywordscohort study / osteoporosis / bone mineral density / DEX / fast bone loser / risk factor / life style / multiple regression analysis
Research Abstract

A cohort study on osteoporosis was performed in two communities with different characteristics in Wakayama prefecture in order to determine the distribution of bone mineral density (BMD) and the incidence of fast bone losers of lumber BMD by sex and age, and also to clarify factors affecting changes in BMD.In Miyama village, located in a mountainous area, a cohort of 1543 inhabitants aged 40-79 years (716 males and 827 females) was established from a register of inhabitants. In Taiji town, located in a seaside area, another cohort of 2261 inhabitants aged 40-79 years (1028 males and 1233 females) was identified. Fifty men and 50 women in each age group between 40 and 79 years, a total of 400 participants, were recruited randomly. Initial examination of lumber BMD was carried out in 1990 in Miyama and in 1993 in Taiji. After 3 years, a follow-up study was performed in each area on the same subjects. DEX (Lunar DPX in Miyama, Hologic QDR-1000 in Taiji) was used for the measurement of BMD … More in both the initial and follow-up studies. The BMD was higher in males than in females in any age group and an age-related decrease in BMD was observed in both areas. The BMD was significantly higher in the seasside population compared with mountain population in both sexes in any age group except males in their 50s. Changes in mean lumber BMD during 3-year period were compared by sex and age. In men, almost no rate of change in BMD was observed. By contrast, in women, a decrease in BMD was observed. The incidence of fast bone losers was 2.4% in men and 9.7% in women in Miyama village ; in Taiji town, it was 2.2% in men and 6.9% in women. Factors affecting annual changes in BMD were also investigated with a cohort study and analyzed by multiple regression analysis. The following items were significantly related to annual changes in BMD : medication with tranquillizer in both sexes, milk consumption in males, body weight and height at the initial measurement, and small fish consumption in females. Partial regression coefficients for menopause and the post menopausal period were also significant in females. Less

Report

(4 results)
  • 1997 Annual Research Report   Final Research Report Summary
  • 1996 Annual Research Report
  • 1995 Annual Research Report
  • Research Products

    (30 results)

All Other

All Publications (30 results)

  • [Publications] Tsutomu Hashimoto: "Prevalence of vertebral fractures in a rural Japanese population" Journal of Epidemiology. 5(4). 171-175 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 橋本 勉: "骨密度に影響を及ぼす要因に関する検討-和歌山県一地域における骨密度調査より-" 日本公衆衛生雑誌. 43(1). 50-61 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 橋本 勉: "和歌山県下一漁村住民の骨密度調査(第2報)骨密度に影響を与える要因の分析" 日本衛生学雑誌. 51(3). 677-684 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 橋本 勉: "疫学調査による大腿骨頸部骨折の実態とその予防" 理学療法. 14(3). 206-211 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Tsutomu Hashimoto: "Nationwide incidence survey of femoral neck fracture in Japan,1992" Journal of Bone and Mineral Metabolism. 15. 100-106 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Tsutomu Hashimoto: "Epidemiology of osteoporosis in Japan" Osteoporosis International. 7(Suppl.3). S99-S102 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 橋本 勉: "骨粗鬆症って何?" 厚生社, 148 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 橋本 勉: "骨代謝とQOL 骨と日常生活" 医薬ジャーナル社, 232 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Tsutomu Hashimoto: "Prevalence of vertebral fractures in a rural Japanese population" Journal of Epidemiology. 5(4). 171-175 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Tsutomu Hashimoto: "A population based study on factors related to bone mineral density in Wakayama Prefecture" Japanese Journal of Public Health. 43(1). 50-61 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Tsutomu Hashimoto: "A population survey on bone mineral density in a fishing village in Wakayama Prefecture (Part 2) ; The analysis of the risk factors affecting the bone mineral density" Japanese Journal of Hygiene. 51(3). 677-684 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Tsutomu hashimoto: "Epidemiology and prevention of hip fracture" Rigakuryohou. 14(3). 206-211 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Tsutomu Hashimoto: "Nationwide incidence survey of femoral neck fracture in Japan, 1992" Journal of Bone and Mineral Metabolism. 15. 100-106 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Tsutomu Hashimoto: "Epidemiology of osteoporosis in Japan" Osteoporosis International. 7(Suppl.3). S99-S102 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 橋本勉 他: "疫学調査による大腿骨頚部骨折の実態とその予防" 理学療法. 14(3). 206-211 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 吉村典子 他: "Fast bone loserの出現頻度ー山村と漁村の比較ー" Osteoporosis Japan. 5(2). 231-234 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 森岡聖次 他: "骨粗鬆症予防のための生活習慣の検討" Osteoporosis Japan. 5(3). 555-560 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] T.Hashimoto et.al.: "Epidemiology of Osteoporosis in Japan" Osteoporosis International. 7(Suppl.3). S99-S102 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 上田晃子 他: "骨密度に影響を及ぼす要因に関する検討" 日本公衆衛生雑誌. 43 (1). 50-61 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 笠松隆洋 他: "和歌山県下一漁村住民の骨密度調査(第1報)地域代表性のある集団での性・年齢別骨密度値" 日本衛生学雑誌. 50 (6). 1084-1092 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 橋本勉: "骨粗鬆症における疫学調査の方法" Osteoporosis Japan. 4 (1). 73-87 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 吉村典子 他: "環境の異なる2地域における骨代謝マーカー分布-山村と漁村の比較-" Osteoporosis Japan. 4 (2). 119-122 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 森岡聖次 他: "骨量の地域差-山村と漁村の比較-" CLINICAL CALCIUM. 6 (7). 29-33 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Yoshimura N. et al.: "Bone metabolic marker levels in residents of a rural community in Japan" Journal of Bone and Mineral Metabolism. 14. 39-42 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 吉村典子 他: "和歌山県下-漁村住民の骨密度調査(第2報)骨密度に影響を与える要因の分析" 日本衛生学雑誌. 51 (3). 677-684 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 橋本 勉: "骨代謝とQOL" 医薬ジャーナル社, 230 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 橋本 勉: "骨粗鬆症Q & A" 医薬ジャーナル社, 167 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 上田晃子,他: "骨密度に影響を及ぼす要因に関する検討" 日本公衆衛生雑誌. 43. 50-61 (1996)

    • Related Report
      1995 Annual Research Report
  • [Publications] 笠松隆洋,他: "和歌山県下一漁村住民の骨密度調査(第1報)" 日本衛生学雑誌. 50. 1084-1092 (1996)

    • Related Report
      1995 Annual Research Report
  • [Publications] 橋本勉: "骨粗鬆症における疫学調査の方法" Osteoporosis Japan. 4. 73-87 (1996)

    • Related Report
      1995 Annual Research Report

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Published: 1995-04-01   Modified: 2016-04-21  

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