| Project/Area Number |
07458009
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
体育学
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| Research Institution | University of Tsukuba |
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Principal Investigator |
KATSUTA Shigeru University of Tsukuba, Institute of Health and Sport Sciences. Professor, 体育科学系, 教授 (70038446)
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| Co-Investigator(Kenkyū-buntansha) |
INAKI Mitsuharu University of Tsukuba, Institute of Health and Sport Sciences.Assistant Research, 体育科学系, 助手 (20261787)
OHMORI Hajime University of Tsukuba, Intitute of Health and Sport Sciences.Assistant Professor, 体育科学系, 講師 (20223969)
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| Project Period (FY) |
1995 – 1997
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| Project Status |
Completed (Fiscal Year 1997)
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| Budget Amount *help |
¥6,500,000 (Direct Cost: ¥6,500,000)
Fiscal Year 1997: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1996: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 1995: ¥4,000,000 (Direct Cost: ¥4,000,000)
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| Keywords | capillary / heart muscle / skeletal muscle / cardiac hypertrophy / endurance training / 持久性トレーニング / 毛細血管床 / スポーツ心臓 / ラット / 左心室壁 |
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| Research Abstract |
The aim of this study was to examine the morphological adaptation of capillary network on heart and skeletal muscles in the exercised rats by examining both the capillary number and the luminal area. All capillary parameters were determined using morphometric methods in perfusion-fixed muscles. The following results were obtained :
In heart muscle, the high-intensity endurance training causes enlargement of the capillary luminal area, while neither the low-nor the high-intensity endurance training stimulate the proliferation of capillaries. The size of capillary surface in the endurance training-induced cardiac hypertrophied muscle was kept equivalent to normal heart muscle by enlargement of capillary luminal area.
In skeletal muscle, the capillaries number in both the low-and the high-intensity endurance trained muscle were significantly higher than the normal control muscle. Number of capillaries with small luminal diameter (2-4 mum) was significantly higher in low-intensity endurance trained muscle than in normal muscle. In contrast, high-intensity endurance trained muscle had significantly higher number of capillaries with large luminal diameter (8-10 mum) compared with normal muscle. This results indicate that endurance training induces changes in capillary luminal diameter as well as capillary number, and that the adaptive response of capillary luminal diameter to endurance training depend on training intensity.
These findings connote that number of capillary and capillary luminal area should be taken into account in morphological assessment of capillary.
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