| Project/Area Number |
07555402
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
Intelligent mechanics/Mechanical systems
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| Research Institution | Nagoya University |
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Principal Investigator |
IKUTA Koji Nagoya Univ.Grad.Sch.Eng.Prof., 工学研究科, 教授 (90212745)
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| Project Period (FY) |
1995 – 1997
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| Project Status |
Completed (Fiscal Year 1997)
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| Budget Amount *help |
¥2,400,000 (Direct Cost: ¥2,400,000)
Fiscal Year 1997: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1996: ¥1,400,000 (Direct Cost: ¥1,400,000)
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| Keywords | biochemical IC / MIFS / Cell free synthesis of protein / Luciferase / micro reactor / DNA synthesis / 無細胞タンパク合成 / ルミノール反応 / スーパーIHプロセス / 紫外線硬化樹脂 / 大量生産形光造形法 / 光ファイバーアレイ / ポリマーサーミスター / ポリマーサーミスタ / ポリマー熱電対 |
|---|
| Research Abstract |
We have developed several types of biochemical IC Chips with photo detective micro reactor named "MIFS (Micro Integrated Fluid System)". The real time monitoring and controlling cell free synthesis of protein was demonstrated successfully. The photo protein of firefly so called Luciferase was synthesized. The biochemical luminescence was monitored by built-in photo diode in the micro reactor to transfer reaction status into voltage signal. Feedback control synthetic reaction was verified experimentally. The results achieved here should be key technology for future DNA and RNA synthesis without biological cell.
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