| Project/Area Number |
07557116
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
Functional basic dentistry
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| Research Institution | TOHOKU UNIVERSITY |
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Principal Investigator |
YAMADA Tadashi Tohoku Univ.Sch.of Dent.Professor, 歯学部, 教授 (50005021)
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| Co-Investigator(Kenkyū-buntansha) |
ABBE Kazuhiko Tohoku Univ.Sch.of Dent.Associate Professor, 歯学部, 助教授 (40151089)
TAMAZAWA Yoshinori Tohoku Univ.Dent.Hosp.Lecturer, 歯学部附属病院, 講師 (10124603)
WATANABE Makoto Tohoku Univ.Sch.of Dent.Professor, 歯学部, 教授 (80091768)
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| Project Period (FY) |
1995 – 1997
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| Project Status |
Completed (Fiscal Year 1997)
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| Budget Amount *help |
¥6,800,000 (Direct Cost: ¥6,800,000)
Fiscal Year 1997: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 1996: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1995: ¥4,300,000 (Direct Cost: ¥4,300,000)
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| Keywords | Foods / Dental-caries / Indwelling-electrode / Sugar-substitutes / pH-in-plaque / Cariogenicity / Saliva / Medicine / 微小トランジスタ(ISFET)電極 / 食品のう蝕誘発性 / 酸産生性 / 歯垢 / 歯垢pHの変化 / う蝕 / 食品の齲蝕誘発性 / 代用糖 / ISFET電極 / 歯垢細菌 / 糖代謝 |
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| Research Abstract |
We developed the practical system to measure the in vivo interdental plaque-pH of low molar teeth in humans using an indewelling electrode. Our methods and data were compared with those of three test laboratories authorized by Toothfriendly Sweets International. After a careful investigation our research group is approved and registered as the fourth test laboratory. Several foods and oral medicines were tested practically by our indwelling system. Most of throat lozenges and cough-and-cold medicated syrups availabe in Japan turned out to be acidogenic. Their fermentative sugars should be substituted by non-or low-acidogenic sweetners to reduce their cariogenic potential. Our research work is expected to provide social profits in cooperation with suitable confectionery and pharmaceutical companies. The importance of salivary role was practically demonstrated in keeping in vivo plaque-pH high. It is important to think about what to eat, how to eat and when to eat in order to prevent dental caries practically. This research work makes possible to present concrete information on acidogenicity of foods when and how they are taken. The careful consideration of eating habits in preventing dental caries are made an appeal not only to the professional field but also to the general public through the mass media such as news papers etc.
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