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Development of Education and Research Support System for Human Embryology using Three-Dimensional Fetus Image Reconstruction

Research Project

Project/Area Number 07557182
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section試験
Research Field General anatomy (including Histology/Embryology)
Research InstitutionKYOTO UNIVERSITY

Principal Investigator

KOMORI Masaru  Research Institute of Medicine, Lecturer, 医学研究科, 講師 (80186824)

Co-Investigator(Kenkyū-buntansha) MINATO Kotaro  Research Institute of Medicine, Associate Professor, 医学研究科, 助教授 (00127143)
TAKAHASHI Takashi  Research Institute of Medicine, Professor, 医学研究科, 教授 (40055992)
SHIOTA Kouhei  Research Institute of Medicine, Professor, 医学研究科, 教授 (80109529)
Project Period (FY) 1995 – 1996
Project Status Completed (Fiscal Year 1996)
Budget Amount *help
¥2,900,000 (Direct Cost: ¥2,900,000)
Fiscal Year 1996: ¥2,900,000 (Direct Cost: ¥2,900,000)
Keywordscontinuous fetus sections / 3D image reconstruction / human embryology / development process / multimedia / network / ネットワーク / コンピュータグラフィックス / 画像処理 / 三次元画像 / 顕微鏡画像 / WWW / 胎児 / 胚子
Research Abstract

This research is aimed for development of a system that acquires digital data of fetus specimen, reconstructs 3D image from them and visualizes in various way.
In the first step (1995), image acquisition system from a microscope was developed. The XY-stage of a microscope was modified to be able to rotate, so that a specimen image was aligned rapidly under overlaid display of continuous slices. Comparing with a photograph which was prepared before the fetus had been sliced, those acquired image set were adjusted more precisely.
In the second step (1996), the visualization system of 3D image was developed. Not only simple surface image of body and organs but also overlaid 3D image organs with transparent body surface can be displayed. Virtual section image in arbitrary direction of reconstructed 3D image can be viewed. Some of those image were picked up and put on a WWW server (The URL is http : //www.kuhp.kyoto-u.ac.jp/VE/). Selected image and movie were recorded into VCR tape and used in a lecture of anatomy for medical students. The whole slice image were acquired for nine normal human fetus specimen in Carnegie Stage 13 to 23, 3D image of body, inner ear, neural tube and heart are reconstructed.
A trial of synthesis of growing process using several actual image data is in a prototype stage yet. Analysis of the difficulties is still undergoing. This system is based on NIH Image software with several modifications.

Report

(3 results)
  • 1996 Annual Research Report   Final Research Report Summary
  • 1995 Annual Research Report
  • Research Products

    (14 results)

All Other

All Publications (14 results)

  • [Publications] 小森 優: "ヒト発生学のための研究教育支援システムVirtual Embryology" 第11回生体・生理工学シンポジウム論文集 BPES'96. 57-60 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] "ヒト胚子の立体像再構成と発生過程の仮想的再現" 医用電子と生体工学. 34. 337 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] M.Komori: "Virtual Embryology: A 3D Library Reconstructed from Human Embryo Sections and Animation of Development Process" MEDINFO95. 1229 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 三浦 岳: "コンピュータグラフィクスによるヒト胚子連続切片からの三次元立体画像の再構築" 解剖学雑誌. 70. 353-361 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] M.Komori, et al.: "A Research and Education Support System for Human Embryology-VIRTUAL EMBRYOLOGY-" Proceedings of the 11th Bio and Physio-Engineering Symposium, BPES'96 (Japanese). 57/60. (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] M.Komori, et al.: "Three Dimensional Reconstruction of Human Embryo image and Presentation of Virtually Growing Process" Japanese Journal of Medical and Biological Engneering. 34. 337 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] M.Komori, et al.: "Virtual Embryology : A 3D Library Reconstructed from Human Embryo Sections and Animation of Development Process" MEDINFO95. 1229. (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] T.Miura, et al.: "Reconstruction of Three Dimentional Image from Human Fetus Sections Using Computer Graphics" Japanese Journal of Anatomy. 70. 353/361 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] M.Komori,et al: "VIRTUAL EMBRYOLOGY : 3D LIBRARY RECONSTRUCED FROM HUMAN EMBRYO SECTIONS AND ANIMATION OF DEVELOPMENT PROCESS" PROCEEDINGS OF THE EIGHTH WORLD CONGRESS ON MEDICAL INFORMATICS (MEDINFO'95). 1229- (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] 三浦岳、他: "コンピュータグラフィックスによるヒト胚子連続切片からの三次元立体像の再構築" 解剖学雑誌. 70. 353-361 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] 小森優、他: "ヒト胚子の立体像再構成と発生過程の仮想的再現" Japanese Journal of Medical Electronics and Biological Engneering. 34 suppl、. 337- (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 小森優、他: "ヒト発生学のための研究教育支援システムVirtual Embryology" 第11回生体生理工学シンポジウム論文集. BPES'96. 57-60 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] M. Komori, et al: "VIRTUAL EMBRYOLOGY: 3D LIBRARY RECONSTRUCED FROM HUMAN EMBRYO SECTIONS AND ANIMATION OF DEVELOPMENT PROCESS" PROCEEDINGS OF THE EIGHTH WORLD CONGRESS ON MEDICAL INFORMATICS (MEDINFO'95). 1229- (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 三浦 岳、他: "コンピュータグラフィックスによるヒト胚子連続切片からの三次元立体像の再構築" 解剖学雑誌. 70. 353-361 (1995)

    • Related Report
      1995 Annual Research Report

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Published: 1996-04-01   Modified: 2021-12-07  

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