• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

The effect of chloroform and trichloroethane on the respiration and circulation

Research Project

Project/Area Number 07557219
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section試験
Research Field Legal medicine
Research InstitutionYamagata University School of Medicine

Principal Investigator

SUZUKI Tsuneo  Yamagata University School of Medicine, Department of Forensic Medicine, Professor, 医学部, 教授 (70004588)

Co-Investigator(Kenkyū-buntansha) TAKAHASHI Hiroshi  Yamagata University School of Medicine, Department of Forensic medicine, Assista, 医学部, 助手 (10142217)
UMETSU Kazuo  Yamagata University School of Medicine, Department of Forensic Medicine, Assista, 医学部, 助教授 (10091828)
Project Period (FY) 1995 – 1996
Project Status Completed (Fiscal Year 1996)
Budget Amount *help
¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 1996: ¥2,300,000 (Direct Cost: ¥2,300,000)
KeywordsToxicology / Chloroform / Trichloroethane / Inhalation / Respiration / Circulation
Research Abstract

Chloroform and trichloroethane has been occasionally used for not only abuse, suicide and homicide but also for incapacitation of a victim for rape or robbery. To investigate the course of respiration and circulation during chloroform or trichloroethane inhalation, dogs were allowed to breathe highly concentrated chloroform or trichloroethane vapor. In chloroform inhalation, the respiratory movements ceased in 1.0-1.5 min. The BP began to reduce in 10 sec after the chloroform inhalation and the circulatory breakdown occurred with the cessation of respiratory movement. A few animals showed several transient arrhythmia in the beginning of decrease of BP.Some dogs were allowed to breathe concentrated chloroform vapor for 40-50 sec.They recovered, and their reactions to stimuli could not be seen for 10-15 min after the cessation of chloroform inhalation. In trichloroethane inhalation, the course of respiration and circulation was similar to that in chloroform, though in trichloroethane inhalation, it took a little longer time to cause respiratory and circulatory breakdown than in chloroform. These results suggested that the cause of death from inhalation of highly concentrated chloroform or trichloroethane is the direct depression action both on the respiratory center and the heart and that the inhalation of highly concentrated chloroform or trichloroethane vapor with a saturated cloth over the victim's face for 40-50 sec can probably incapacitate a victim for at least 10-15 min.

Report

(3 results)
  • 1996 Annual Research Report   Final Research Report Summary
  • 1995 Annual Research Report
  • Research Products

    (4 results)

All Other

All Publications (4 results)

  • [Publications] Tsuneo Suzuki: "The course of respiration and circulation in Chloroform inhalation" Forensic Science International. (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] "The course of respiration and circulation in chloroform Inhalation" Forens.Sci.Internat.(1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Tsuneo Suzuki: "The course of respiration and circulation in Chloroform inhalation" Forensic Science International. (1997)

    • Related Report
      1996 Annual Research Report
  • [Publications] 鈴木,庸夫: "クロロホルム吸引時の呼吸・循環の経過" 日本法医学雑誌. 50. (1996)

    • Related Report
      1995 Annual Research Report

URL: 

Published: 1996-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi