Development of a new tissue conditioner possessed of an antibacterial/-fungal effect
| Project/Area Number |
07557273
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 試験 |
|---|
| Research Field |
補綴理工系歯学
|
|---|
| Research Institution | HIROSHIMA UNIVERSITY |
|---|
Principal Investigator |
AKAGAWA Yasumasa Hiroshima Univ., Sch.of Dentistry, Professor, 歯学部, 教授 (00127599)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
ABE Yasuhiko Hiroshima Univ., Sch.of Dentistry, Research Assistant, 歯学部, 助手 (00253097)
KUBO Takayasu Hiroshima Univ., Sch.of Dentistry, Research Assistant, 歯学部, 助手 (60240876)
岩本 義史 広島大学, 歯学部, 教授 (90034165)
佐藤 裕二 広島大学, 歯学部, 助教授 (70187251)
|
|---|
| Project Period (FY) |
1995 – 1996
|
| Project Status |
Completed (Fiscal Year 1996)
|
| Budget Amount *help |
¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1996: ¥700,000 (Direct Cost: ¥700,000)
|
|---|
| Keywords | antimicrobial effect / tissue conditioner / silver-zeolite / dynamic viscoelastic property |
|---|
| Research Abstract |
The purpose of the first study was to elucidate the in vitro antimicrobial effect of five commercially available tissue conditioners containing silverzeolite (2 wt%) on Candida albicans and nosocomial respiratory infectioncausing bacteria, Staphylococcus aureus and Pseudomonas aeruginosa. Tissue conditioners containing silver-zeolite have been shown to have antimicrobial effects for 4 weeks on C.albicans and nosocomial respiratory infection-causing bacteria in saliva in vitro.
The purpose of the second study was to evaluate dynamic viscoelastic properties of same five tissue conditioners containing silver-zeolite (0.2.5 and 10 wt%) using non-resonance forced vibration method. Measurements were carried out after without and with immersion in distillled water and artificial saliva at 37ﾟC for 24 hours, 1 week and 4 weeks. The results indicate that dynamic viscoelastic properties of tissue conditioners are influenced considerably by storage conditions and the time proceeds, and that there is a small effect of silver-zeolite.
|
Report
(3 results)
Research Products
(22 results)
