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The Development and The Clinical Application of The Total Respiratory Center Function Test

Research Project

Project/Area Number 07557320
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section試験
Research Field Laboratory medicine
Research InstitutionHIROSHIMA UNIVERSITY

Principal Investigator

KAMBE Masayuki  Hiroshima University, School of Medicine, Professor, 医学部, 教授 (70034139)

Co-Investigator(Kenkyū-buntansha) KIMURA Toshiki  Hiroshima University, Dental Hospital, Research Associate, 歯学部・附属病院, 助手 (00253104)
MORISHITA Kazuhiko  Hiroshima University, School of Medicine, Assistant Professor, 医学部, 講師 (60239647)
Project Period (FY) 1995 – 1996
Project Status Completed (Fiscal Year 1996)
Budget Amount *help
¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 1996: ¥1,800,000 (Direct Cost: ¥1,800,000)
KeywordsP0.1 / RESPIRATORY CENTER / RESPIRATORY CONTROL / AIRWAY OCCLUSION PRESSURE / 呼吸反射テスト / 機械的受容器 / 化学受容器 / 呼吸中枢機能 / 気道抵抗 / 胸郭抵抗 / 呼気NOガス / 睡眠時無呼吸症候群
Research Abstract

We developed the new automatic machine to measure the respiratory functions which is in brain stem.
This machine is composed two manometers to measure the airway occlusion pressure and the air flow of mouth included computer tips and one recorder.
The principle of this machine is due to the inspiratory phase of breath is activated by N.Vagus from the respiratory center.
We know already the respiratory center controls the breath based on the change of inter pressure of chest wall which can moves the lungs.
By using of this new machine, we could analyze airway occlusion pressure duaring full inspiratory phase, P<@D20.1@>D2 (airway occlusion pressure at 0.1 secounds) and breath curves. So, we could analyze not only P<@D20.1@>D2 but the switch mechanism between inhale and exhale of breath among patients with some respiratory diseases. Specially, we could have an interesting result P<@D20.1@>D2 of non-attached bronchial asthma cases (28.0(]SY.+-。[)7.5mmH<@D22@>D2o) is more than P<@D20.1@>D2 of normal cases (17.6(]SY.+-。[)4.7mmH<@D22@>D2o). Although we must study the mechanisms of increasing of P<@D20.1@>D2 of non-attached bronchial asthma cases, we believe this machine is useful for patients with respiratory diseases.

Report

(3 results)
  • 1996 Annual Research Report   Final Research Report Summary
  • 1995 Annual Research Report
  • Research Products

    (8 results)

All Other

All Publications (8 results)

  • [Publications] 木村俊樹: "睡眠呼吸障害モデルにおける循環動態に関する研究" 日本胸部疾患学会雑誌. 33. 3-9 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 神辺眞之,木村俊樹(分担): "標準臨床検査ガイド'97" 南山堂, 359 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] T.Kimura: "Study on Circulation Status of Sleep Apnea Model" Journal of Japan Chest Diseases. 33,1. 3-9 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] M.Kambe, T.Kimura: "Arterial Blood Gas" Standard Clinical Laborstory Guid'97. 215-219 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 神辺眞之,木村俊樹(分担): "標準臨床検査ガイド'97" 南山堂, 359 (1997)

    • Related Report
      1996 Annual Research Report
  • [Publications] 木村俊樹: "生理 ポリソムノグラフィー" Laboratory and Clinical Practice. 13. 20-22 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 神辺眞之: "日常初期診療における臨床検査の使い方-呼吸器疾患-" 日本臨床病理学会, 18 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 神辺眞之: "臨床検査ガイド'95(動脈血ガス関係)" 文光堂, 1-43 (1995)

    • Related Report
      1995 Annual Research Report

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Published: 1996-04-01   Modified: 2016-04-21  

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