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Development of a new mobile accelerator for IORT

Research Project

Project/Area Number 07557349
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section展開研究
Research Field Radiation science
Research InstitutionUniversity of Tokyo

Principal Investigator

AOKI Yukimasa (1997)  University of Tokyo, Radiology, Associate Professor, 医学部・附属病院, 助教授 (40143474)

佐々木 康人 (1995-1996)  東京大学, 医学部・附属病院, 教授 (80081694)

Co-Investigator(Kenkyū-buntansha) HIRAOKA Masahiro  University of Kyoto, Radiology, Professor, 医学部・附属病院, 教授 (70173218)
NAGAWA Hirokazu  University of Tokyo, Surgery, Associate Professor, 医学部・附属病院, 助教授 (80228064)
SAITO Hideaki  University of Tokyo, Surgery, Associate Professor, 医学部・附属病院, 助教授 (30134555)
HANAOKA Kazuo  University of Tokyo, Anesthesiology, Professor, 医学部・附属病院, 教授 (80010403)
NAKAGAWA Keiichi  University of Tokyo, Radiology, Assistant Professor, 医学部・附属病院, 講師 (80188896)
青木 幸昌  東京大学, 医学部・附属病院, 助教授 (40143474)
澤田 俊夫  東京大学, 医学部(病), 講師 (50143441)
小林 寛伊  東京大学, 医学部(病), 教授 (50010244)
Project Period (FY) 1995 – 1997
Project Status Completed (Fiscal Year 1997)
Budget Amount *help
¥4,400,000 (Direct Cost: ¥4,400,000)
Fiscal Year 1997: ¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 1996: ¥2,400,000 (Direct Cost: ¥2,400,000)
KeywordsIORT / mobile accelerator / regulation / 漏洩線量 / 管理区域 / 移動型電子線照射装置 / 電子線 / 放射線障害防止法 / X周波数帯加速管
Research Abstract

A mobile linear accelerator unit dedicated for electron beam intraoperative radiation therapy (IORT) has been newly developed. It is planned to be scored in operation area and is transferred to the treatment room when IORT is needed. It is as compact as 1140 kg in weight and 190 cm in height (at the time of transportation) since X-band small accelerator tube is applied. Only electron beams (4,6,9, and 12 MeV) are available with the maximum dose rate of 10 Gy/min at the isocenter. Applicator size ranges from 3 cm to 10 cm in diameter. Gantry rotation of (]SY.+-。[)45 degrees and C-arm rotation of (]SY.+-。[)30 degrees are available for optimal beam placement. Before the clinical trial at the University of California, U.S.A., leakage doses around the facility were measured. During the clinical trial, doses from the operating room on the 4th floor were measured in the adjoining corridor and on the doors around the room and in rooms on the 3rd and 5th floor. The measured maximum dose was 72muSv on the outside surface of the door of the operating room. Although his dose level is lower than the limit determined by the radiaiton protection law, the medical law should be modified for the actual use of the mobile accelerator.

Report

(4 results)
  • 1997 Annual Research Report   Final Research Report Summary
  • 1996 Annual Research Report
  • 1995 Annual Research Report
  • Research Products

    (32 results)

All Other

All Publications (32 results)

  • [Publications] Aoki Y, et al.: "Clinical evaluation of Gamma Knife radiosurgery for intracranial arteriovenoius malformation" Radiation Medicine. 14. 265-268 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Togo M, Aoki Y, et al.: "Gamma Kife radiosurgery for brain stem metastases:Two autopsy cases" Stereotactic Functional Neurosurgery. 66. 225-230 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Aoki Y.et al.: "Dose evaluation of patients receiving totalbody irradiation for the pre-treatment of bone marrow transplantation" Radiation Protection Dosimetry. 71. 61-64 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Nakagawa K, Aoki Y, et al.: "Argatrobanin the treatment of radiation injury of the hand:a case report" Current Therapeutic Research. 58. 323-329 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Nakagawa K, Aoki Y, et al.: "Improvement of Image Quality In Megavoltage Computed Tomography with Second Generation Scanning Mode" Radiation Oncology Investigation. 5. 257-263 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Nakagawa K, Aoki Y, et al.: "High dose conformal radiotherapyinfluenced pattern of failure,but did not improve survival of glioblastoma multiforme" Int J Radiat Oncol Biol Phys. (in print).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Aoki Y,et al: "Clinical evaluation of Gamma knife radiosurgery for intracranial arteriovenoius malformation." Radiation Medicine. 14. 265-268 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Tago M,Aoki Y,et al: "Gamma knife radiosurgery for brain stem metastases : Two autopsy cases" Stereotactic Functional Neurosurgery. 66. 225-230 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Aoki Y,et al: "Dose evaluation of patients receiving total-body irradiation for the pre-treatment of bone marrow transplantation." Radiation Protection Dosimetry. 71. 61-64 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Nakagawa K,Aoki Y,et al: "Argatroban in the treatment of radiation injury of the hand : a case report." Current Therapeutic Research. 58. 323-329 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Nakagawa K,Aoki Y,et al: "Improvement Of Image Quality In Megavoltage Computed Tomography With Second Generation Scanning Mode" Radiation Oncology Investigation. 5. 257-263 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Nakagawa K,Aoki Y,et al: "High dose conformal radiotherapy influenced pattern of failure, but did not improve survival of glioblastoma multiforme" Int J Radiat Oncol Biol Phys. (in print).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 中川恵一, 他: "C-MOS型リアルタイムデジタルX線画像検出装置の開発" 日本医学放射線学会誌. (印刷中).

    • Related Report
      1997 Annual Research Report
  • [Publications] 中川恵一, 他: "小焦点X線拡大撮影システムを用いたラット骨粗鬆症モデルの定量的解析" 先端医学. 4. 52-54 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 中川恵一, 他: "Webブラウザを用いた線量分布画像の観察と管理" 日本医学放射線学会誌. (印刷中).

    • Related Report
      1997 Annual Research Report
  • [Publications] 中川恵一, 他: "原体照射とノンコプラナ照射法" Innervision. 12(10). 86-88 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Nakagawa K, et al.: "High dose conformal radiotherapy influenced pattern of but did not improve survival of glioblastoma multiforme." Int J Radiat Oncol Biol Phys. (in print).

    • Related Report
      1997 Annual Research Report
  • [Publications] 中川恵一, 他: " 術中照射専用可動型電子線照射装置の開発" Innervision. 12(10). 49-52 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 中川恵一,佐々木康人,他: "ノンコプラナ法による高精度放射線治療" 医学のあゆみ. 177. 136-137 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 中川恵一,佐々木康人,他: "治療用電子線またはX線のエネルギー測定の問題点を探る" 日本放射線技術学会雑誌. 52. 425-429 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Sakata K,Sasaki Y,et al: "Radiation therapy for patients with exroderma pigmentosum" Radiation Medicine. 14. 87-90 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 中川恵一,佐々木康人,他: "三次元治療計画の現状と問題点" 新医療. 264. 59-6 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Aoki Y,Sasaki Y,et al: "Clinical evaluation of Gamma knife radiosurgery for intracranial arteriovenoius malformation" Radiation Medicine. 14. 265-268 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 小野木雄三,佐々木康人,他: "電子的照合画像を利用した患者セットアップ精度の解析" 日本放射線腫瘍学会誌. 8. 265-276 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 中川恵一: "原体照射とノンコプラナー照射の利点と問題点" Innervision. 10. 34-40 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 中川恵一: "ガンマナイフ治療の現状と展望" Innervision. 10. 51-54 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Sakata, K: "Evaluation of the results of postoperative radiotherapy for esophaeal cancer" Radiat. Oncol. Invest.3. 81-89 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 中川恵一: "放射線被曝事故における手掌の放射線障害について" アイソトープ. 44. 440-445 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 中川恵一: "超高圧X線CT装置を利用した原体照射の照合法の開発" 日本放射線腫瘍学会誌. 7. 357-361 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 中川恵一: "超高圧X線CTスキャンにおける画質向上に関する研究 第一報:第二世代スキャンによる実験的検討" 日本放射線腫瘍学会誌. 7. 357-361 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 中川 恵一: "癌放射線治療エッセンス" 中外医学社, 177 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 幕内 雅敏: "悪化するがんの治療百科" 三省堂, 303 (1995)

    • Related Report
      1995 Annual Research Report

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Published: 1996-04-01   Modified: 2016-04-21  

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