Study of Mechanism of Decompressible Cavitation Occurrence and Bubble Embolism in Blood
Project/Area Number |
07650213
|
Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Fluid engineering
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Research Institution | Kumamoto University |
Principal Investigator |
TSUJINO Tomoji Kumamoto University, Faculty of Education, Professor, 教育学部, 教授 (80006197)
|
Co-Investigator(Kenkyū-buntansha) |
MIURA Makoto Tohoku University, School of Medicine, Instructor, 医学部, 講師 (50239191)
|
Project Period (FY) |
1995 – 1996
|
Project Status |
Completed (Fiscal Year 1996)
|
Budget Amount *help |
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1996: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1995: ¥1,400,000 (Direct Cost: ¥1,400,000)
|
Keywords | Bubble / Submarine sickness / Gas embolism / Cavitation / Cavity / Gas-liquid two phase flow / Bioengineering / Fluid mechanics / 血液 / ガス拡散 |
Research Abstract |
It is known that decompression disease represented by submarine sickness causes disturbances of peripheral circulation owing to bubble formation in blood. However very little is known about the growth of micro bubble and the mechanism of the development. In this work, as purpose of clarification of physical mechanism of an outbreak of decompression disease, an apparatus for gas-liquid two phase flow with compression or decompression type was made by combinating a micro video device into a high liquid pressure vessel. The following experiments I and II were then carried out. In the experiment I,the occurrence of micro bubble in static liquid caused by the difference of the liquid pressure was studied. (1) The bubbles with radius of 0.5-2.0mm are generated in the liquid. (2) The bubble number density increases by an increment of the difference of liquid pressure. (3) The bubble number density of carbon dioxide is large as compared with air bubble. In the experiment II,the gas-liquid two phase flow in the channel was studied in gas over saturated liquid as working fluid. The following results were obtained. (1) The micro bubbles with radius 20-100mum are generated in the channel, and after the bubbles grow rapidly during 0.6-3sec. The growth rates increase with an additional gas pressure into the liquid. (2) The growth rate of air bubble for flow velocity 0.5m/s is four times as large as for 2.3m/s. (3) The air cavity grows with rate of about 2.4m/s, and the maximum size is 5mm in width and 14mm in length. (4) The diameters of micro carbon dioxide bubbles are 20-200mum. The growth rates of carbon dioxide bubbles are 5-80times as large as the rates of air bubbles.
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Report
(3 results)
Research Products
(13 results)