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Study of Mechanism of Decompressible Cavitation Occurrence and Bubble Embolism in Blood

Research Project

Project/Area Number 07650213
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Fluid engineering
Research InstitutionKumamoto University

Principal Investigator

TSUJINO Tomoji  Kumamoto University, Faculty of Education, Professor, 教育学部, 教授 (80006197)

Co-Investigator(Kenkyū-buntansha) MIURA Makoto  Tohoku University, School of Medicine, Instructor, 医学部, 講師 (50239191)
Project Period (FY) 1995 – 1996
Project Status Completed (Fiscal Year 1996)
Budget Amount *help
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1996: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1995: ¥1,400,000 (Direct Cost: ¥1,400,000)
KeywordsBubble / Submarine sickness / Gas embolism / Cavitation / Cavity / Gas-liquid two phase flow / Bioengineering / Fluid mechanics / 血液 / ガス拡散
Research Abstract

It is known that decompression disease represented by submarine sickness causes disturbances of peripheral circulation owing to bubble formation in blood. However very little is known about the growth of micro bubble and the mechanism of the development. In this work, as purpose of clarification of physical mechanism of an outbreak of decompression disease, an apparatus for gas-liquid two phase flow with compression or decompression type was made by combinating a micro video device into a high liquid pressure vessel. The following experiments I and II were then carried out.
In the experiment I,the occurrence of micro bubble in static liquid caused by the difference of the liquid pressure was studied.
(1) The bubbles with radius of 0.5-2.0mm are generated in the liquid. (2) The bubble number density increases by an increment of the difference of liquid pressure. (3) The bubble number density of carbon dioxide is large as compared with air bubble.
In the experiment II,the gas-liquid two phase flow in the channel was studied in gas over saturated liquid as working fluid. The following results were obtained.
(1) The micro bubbles with radius 20-100mum are generated in the channel, and after the bubbles grow rapidly during 0.6-3sec. The growth rates increase with an additional gas pressure into the liquid. (2) The growth rate of air bubble for flow velocity 0.5m/s is four times as large as for 2.3m/s. (3) The air cavity grows with rate of about 2.4m/s, and the maximum size is 5mm in width and 14mm in length. (4) The diameters of micro carbon dioxide bubbles are 20-200mum. The growth rates of carbon dioxide bubbles are 5-80times as large as the rates of air bubbles.

Report

(3 results)
  • 1996 Annual Research Report   Final Research Report Summary
  • 1995 Annual Research Report
  • Research Products

    (13 results)

All Other

All Publications (13 results)

  • [Publications] 辻野智二: "狭いすき間内におけるキャビテーション損傷に及ぼすポリマー添加の影響" 日本機械学会第73期全国大会講演論文集. Vol.2. 61-62 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 辻野智二・堀光晴: "高圧力差液中の発泡シミュレーション装置の開発・試作に関する研究" 日本産業技術教育学会九州支部講演論文集. Vol.8. 45-46 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 辻野智二・分山貴志: "ガス過飽和液体中の気泡核分布に関する実験的研究" 日本産業技術教育学会全国大会講演要旨集. Vol.39. 69- (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 辻野智二・堀光晴: "ガス過飽和液体の気液二相流れに関する実験的研究" 日本産業技術教育学会九州支部講演論文集. Vol.9. 11-12 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Tomoji Tsujino: "Effect of polymer Additives on Cavitation Damage in a Narrow Clearance" The 73rd General Meeting of the Japan Society of Mechanical Engineers. 95-10. 61-62 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Tomoji Tsujino: "Study of Development and Test of a Simulation Equipment about Bubble Generation in a Liquid with High Pressure Difference" Kyushu Local Meeting of the Japanese Society of Technology Education. vol.8. 45-46 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Tomoji Tsujino: "Experimental Study of Bubble Nuclei Distribution in Gas Oversaturated Liquids" The 39th General Meeting of the Japanese Society of Technology Education. 69 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Tomoji Tsujino: "Experimental Study of Gas-Liquid Two Phase Flow in Gas Oversaturatid Liquids" Kyushu Local Meeting of the Japanese Society of Technology Education. vol.9. 11-12 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 辻野智二: "狭いすき間内におけるキャビテーション損傷に及ぼすポリマー添加の影響" 日本機械学会第73期全国大会講演論文集. Vol.2. 61-62 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] 辻野智二・堀光晴: "高圧力差液中の発泡シミュレーション装置の開発・試作に関する研究" 日本産業技術教育学会九州支部講演論文集. Vol.8. 45-46 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] 辻野智二・分山貴志: "ガス過飽和液体中の気泡核分布に関する実験的研究" 日本産業技術教育学会全国大会講演要旨集. Vol.39. 69- (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 辻野智二: "ガス過飽和液体の気液二相流れに関する実験的研究" 日本産業技術教育学会九州支部講演論文集. Vol.9. 11-12 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 辻野智二,大橋貴幸: "狭いすき間内におけるキャビテーション損傷に及ぼすポリマー添加の影響" 日本機械学会第73期全国大会講演論文集. 11. 61-62 (1955)

    • Related Report
      1995 Annual Research Report

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Published: 1995-04-01   Modified: 2016-04-21  

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