| Project/Area Number |
07651059
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Tottori University |
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Principal Investigator |
KIJI Jitsuo Tottori, Univ.Fac.of Eng.Prof., 工学部, 教授 (60026002)
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| Co-Investigator(Kenkyū-buntansha) |
OKANO Tamon Tottori Univ.Fac.of Eng.Asso.Prof., 工学部, 助教授 (20112104)
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| Project Period (FY) |
1995 – 1996
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| Project Status |
Completed (Fiscal Year 1996)
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| Budget Amount *help |
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1996: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1995: ¥1,600,000 (Direct Cost: ¥1,600,000)
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| Keywords | Palladium catalyst / Carbonylation / Biphasic reaction / Allylic compound / Heck reaction / アルケニルケトン / ブテノリド / フラノン |
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| Research Abstract |
One serlous probelm of homogeneous catalyst is the separation of the product from the catalyst. Since the hydroformylation of propene under biphasic conditions was commercialized in 1984, two-phase catalysis by transition metal complexes attracts much attention. In the present study carbonylation and the Heck reaction were carried out using Pd/water-soluble phosphine or Pd/triphenylphosphine/phase transfer agent as the catalyst.
1 Carbonylation of allylic halides
Palladium-catalyzed, atmospheric pressure carbonylation of allylic halides under alcohol-potassium carbonate two-phase conditions affords beta, gamma-unsaturated esters.
2 Carbonylative coupling of iodobenzene and propargyl alcohol
The reaction of iodobenzene with 2-methyl-3-butyn-2-ol under aqueous NaOH affords a butenolide in one-pot by successive reactions of carbonylation, reduction, and cyclocarbonylation. It was clarified that the biphasic reaction is a contrast to the homogeneous one.
3 Arylation of ethylene
The arylation of ethylene with aryl halides by phosphine-modified palladium catalysts takes place readily to afford stirenes. A variety of functional monomers were synthesized by this methods.
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