| Project/Area Number |
07670274
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
寄生虫学(含医用動物学)
|
|---|
| Research Institution | Shinshu University |
|---|
Principal Investigator |
SUGANE Kazuo Shinshu University, School of Medicine, professor, 医学部, 教授 (50112488)
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|---|
| Co-Investigator(Kenkyū-buntansha) |
KATO Hisaharu Shinshu University, School of Medicine, assistant, 医学部, 助手 (40281042)
|
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| Project Period (FY) |
1995 – 1996
|
| Project Status |
Completed (Fiscal Year 1996)
|
| Budget Amount *help |
¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 1996: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1995: ¥1,800,000 (Direct Cost: ¥1,800,000)
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| Keywords | Dirofilaria immitis / immunodominant antigen / promoter / Dirotilaria immitis / 犬糸状虫 / 抗原遺伝子 / 遺伝子発現 |
|---|
| Research Abstract |
We characterized the genes (Dg2 and DgK) encoding an immunodominant antigen expressed specifically in larval stage of Dirofilaria immitis, and analyzed the function of promoter region of the gene. Microinjection study using Caenorhabditis elegans, the DgK might be expressed only in digestive tract of the nematode.
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