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Epidemiological study of dry mouth in the elderly -etiology, progress, treatment, recuperation-

Research Project

Project/Area Number 07670421
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionTohoku University

Principal Investigator

SAKAMOTO Maya  Tohoku University, School of Dentistry, Assistant, 歯学部, 助手 (90157686)

Co-Investigator(Kenkyū-buntansha) KURIWADA Shizuko  Tohoku University, School of Dentistry, Assistant, 歯学部, 助手 (60225274)
KOMAI Shinya  Tohoku University, Hospital attached School of Dentistry, Assistant, 歯学部・附属病院, 助手 (90234864)
FURUUCHI Toshi  Tohoku University, School of Dentistry, Assistant, 歯学部, 助手 (50209160)
MARUMO Machiko  Tohoku University, Hospital attached School of Dentistry, Lecturer, 歯学部・附属病院, 講師 (10005027)
SANJO Daisike  Tohoku University, School of Dentistry, Professor, 歯学部, 教授 (70013943)
Project Period (FY) 1995 – 1996
Project Status Completed (Fiscal Year 1996)
Budget Amount *help
¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1996: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1995: ¥500,000 (Direct Cost: ¥500,000)
KeywordsDry mouth / Xerostomia / Elderly / Medication side effect / Epidemiologic Study / Xerostomia
Research Abstract

Dry mouth caused by salivary gland hypofunction is a common disoder in elderly persons. However, there have been no surveys reported of dry mouth of the elderly in Japan. The purpose of this study was to evaluate the prevalence and causes of dry mouth in the elderly. The subjects of the study were 95 elderly persons (men m=31, women n=64), aged 65 to 96 years (mean=78) in 3 homes for senior citizens. We asked them detailed questions about various symptoms related to dry mouth, using a specially designed questionnaire. Then we examined missing tooth, oral mucosal lesions and salivary flow-rate by gum test. The results were as follows :
1. Twenty-three (24.2%) of the subjects noticed subjective sensation of dry mouth. 2. The gum test demonstrated decreased saliva secretion in 48.3% of 89 persons. Severe decreased salivation was observed only in 4 persons (4.5). 3. Out of the 95 subjects, 85 (89.5%) had at least one chronic systemic disease and 62 (65.3%) were taking at least one xerostomic medication, (e, g., antihypertensive drugs, antihistemics, anticholinergic drugs, antidepressants, psychotropic drugs, antiparkinsonian medication, and diuretics). 4. Those who taking three kinds of xerostomic medication were found to have significantly diminished salivation or sensation of dry mouth. 5. Atrophic change of tongue (22.1%), lobulated tongue (24.2%) and angular cheilitis (2.1%) were clinically observed. No disease of the oral mucosa, such as Leukoplakia, Candidiasis, Oral lichen planus or Aphthous ulcers, were observed.

Report

(3 results)
  • 1996 Annual Research Report   Final Research Report Summary
  • 1995 Annual Research Report
  • Research Products

    (7 results)

All Other

All Publications (7 results)

  • [Publications] 阪本真弥: "高齢者の口腔乾燥症に関する疫学調査研究" 老年歯科医学. 11. 81-87 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 阪本真弥: "シェ-グレン症候群の口唇腺病理所見と耳下腺造影所見の不一致例の検討" 東北大学歯学雑誌. 15. 1-7 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Maya Sakamoto: "Epidemiological study of dry mouth in the elderly" J J Gerodont. 11. 81-87 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Maya Sakamoto: "The discrepancies between histopathologic (labial glands) and sialographic (parotid glands) findings in Sjogren's syndrome"

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 阪本真弥: "高齢者の口腔乾燥症に関する疫学調査研究" 老年歯科医学. 11・2. 81-87 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 阪本真弥: "シエ-グレン症候群の口唇腺病理所見と耳下腺造影所見の不一致例の検討" 東北大学歯学雑誌. 15・1. 1-7 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 坂本真弥: "高齢者の口腔乾燥症に関する疫学調査研究" 日本口腔診断学会雑誌. 9巻2号(発表予定). (1996)

    • Related Report
      1995 Annual Research Report

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Published: 1995-04-01   Modified: 2016-04-21  

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