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Relationship of levels of personal exposure with ambient concentrations and levels of biological determinants in workers exposed to organic solvents

Research Project

Project/Area Number 07670469
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionKawasaki University of Medical Welfare

Principal Investigator

OGATA Masana  Kawasaki University of Medical Welfare Faculty of Medical Welfare Professor, 医療福祉学部, 教授 (70032844)

Co-Investigator(Kenkyū-buntansha) SHIMADA Yoshihiro  Chugoku Junior College Department of Home Economics Assistant professor, 生活学科, 助教授 (80196493)
FUJII Toshiko  Kawasaki University of Medical Welfare Faculty of Medical Professions Professor, 医療技術学部, 教授 (70099638)
TAGUCHI Toyohiro  Kawasaki University of Medical Welfare Faculty of Medical Welfare Assistant prof, 医療福祉学部, 助教授 (30197248)
Project Period (FY) 1995 – 1996
Project Status Completed (Fiscal Year 1996)
Budget Amount *help
¥1,900,000 (Direct Cost: ¥1,900,000)
Fiscal Year 1996: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1995: ¥1,400,000 (Direct Cost: ¥1,400,000)
KeywordsBiological monitoring / Organic solvent / Urinary solvent / Urinary metabolite / Breath zone air / Mixed solvent / hippuric acid. / Head space gas / 環境濃度 / 個人暴露濃度 / トルエン
Research Abstract

To investigate the relationship among stationary monitoring and personal monitoring in workplaces using solvent mixture (survey 1) and single toluene (survey 2), three sets of air samples were taken. A first set of samples (WP) was taken at many points equally distributed in the workplace to get an average value by A sampling. A second set (PW) was obtained from places proximity of the workers, a third set (BZ) was secured from the breathing zone of the workers. In both surveys, close correlation were found among the concentrations for each air sampling, i.e. there was a close relationship when comparing (PW) to (BZ) and (WP) to (BZ). In survey 2, there was also a close relationship of the concentration of toluene in the air of (BZ) or (WP) with the concentration of toluene and hippuric acid in the urine of the workers. The results suggest that the concentration of solvents in the places proximity of workers is a useful indicator of the amount of exposure to workers who remained same place most of their working time.

Report

(3 results)
  • 1996 Annual Research Report   Final Research Report Summary
  • 1995 Annual Research Report
  • Research Products

    (20 results)

All Other

All Publications (20 results)

  • [Publications] Masana Ogata: "Evaluation of exposure to solvents from their urinary excretions in workers coexposed to toluene,xylene and MIBK" Appl.Occup.Eniron.Hygiene. 10(11). 913-920 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Masana Ogata: "Evaluation of exposure to mixed solvents by analyzing their metabolites and solbents in urine" Kawasaki J.Med.Welfare. 1(1). 1-15 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Hiromi Michitsuji: "Relationship between the ambient concentration of toluene in the air of workplaces and the concentration of toluene or its metabolites" Kawasaki J.Med.Welfare. 1(1). 95-101 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Hiromi Michitsuji: "Desorption of Organic Solvents from Activated Charcoal with 2-Hydroxypyridine" Kawasaki J.Med.Welfare. 1(1). 103-110 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Masana Ogata: "Large scale biological monitoring in Japan" Kawasaki J.Med.Welfare. 2(1). 1-16 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Hiromi Michitsuji: "Relationship between the ambient concentration of mixed solvents in workplaces and the concentration of solvents in breathing zone of worker" Kawasaki J.Med.Welfare. 2(2). 83-89 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Ogata M.: "Evaluation of exposure to solvents from their urinary excretions in workers coexposed to toluene, xylene and MIBK" Appl. Occup. Environ. Hyg.10 (11). 913-920 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Ogata M.: "Evaluation of exposure to mixed solvents by analyzing their metabolites and solvents in urine" Kawasaki J.Med. Welfare. 1 (1). 1-15 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Michitsuji H.: "Relationship between the ambient concentration of toluene in the air of workplaces and the concentration of toluene or its metabolites" Kawasaki J.Med. Welfare. 1 (1). 95-101 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Nichitsuji H.: "Desorption of organic solvents from activated charcoal with 2-hydroxypyridine" Kawasaki J.Med. Welfare. 1 (1). 103-110 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Ogata M.: "Large scale biological monitoring in Japan" Kawasaki J.Med. Welfare. 2 (1). 1-16 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Michitsuji H.: "Relationship between the ambient concentration of mixed solvents in workplaces and the concentration of solvents in breathing zone of worker" Kawasaki J.Med. Welfare. 2 (2). 83-89 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Ogata M.: "Large scale biological monitoring in Japan" Science Total Environ. (in press). (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Masana Ogata: "Large scale biological monitoring in Japan" Kawasaki J.Med.Welfare. 2(1). 1-16 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Hiromi Michitsuji: "Relationship between the ambient concentration of mixed solvents in workplaces and the concentration of solvents in breathing zone of worker" Kawasaki J.Med.Welfare. 2(2). 83-89 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Masana Ogata: "Large scale biological monitoring in Japan" Science of the Total Environment. (in press). (1997)

    • Related Report
      1996 Annual Research Report
  • [Publications] Masana Ogata: "Evaluation of exposure to solvents from their urinary excretions in workers coexposed to toluene, xylene and MIBK" Appl. Occup. Environ. Hygiene. 10(11). 913-920 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Masana Ogata: "Evaluation of exposure to mixed solvents by analyzing their metabolites and solvebts in urine" Kawasaki J. Med. Welfare. 1(1). 1-15 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Hiromi Michitsuji: "Relationship between the ambient concentration of toluene in the air of workplaces and the concentration of toluene or its metabolites in the urine of workers" Kawasaki J. Med. Welfare. 1(1). 89-95 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Hiromi Michitsuji: "Desorption of Organic Solvents from Activated Charcoal with 2-Hydroxypyridine" Kawasaki J. Med. Welfare. 1(1). 97-104 (1995)

    • Related Report
      1995 Annual Research Report

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Published: 1995-04-01   Modified: 2016-04-21  

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