| Project/Area Number |
07671036
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kansai Medical University |
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Principal Investigator |
HARIMA Keizou Kansai Medical University Faculty of Medicine, Assistant Professor, 医学部, 助手 (20121973)
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| Co-Investigator(Kenkyū-buntansha) |
KAWA Soukichi Kansai Medical University, Faculty of Medicine,, Assistant Professor, 医学部, 講師 (30152896)
AKAGI Kiyoshi Kansai Medical University, Faculty of Medicine, Assistant Professor, 医学部, 講師 (30098115)
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| Project Period (FY) |
1995 – 1996
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| Project Status |
Completed (Fiscal Year 1996)
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| Budget Amount *help |
¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 1996: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1995: ¥1,600,000 (Direct Cost: ¥1,600,000)
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| Keywords | esphageal cancer / cavitary thermoradiation therapy / micro selectron / 腔内加温療法 / 腔内放射線療法 / 放射線障害 / 温熱効果 / 正常粘膜組織 |
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| Research Abstract |
In this study, We invesgated the effectiveness of intra cavitary thermoradiation therapy for local advanced esophageal cancer. (2 stage "II", 7 stage "III", 2 stage "IV") For selective irradiating of esophagus, micro selectron HDRIr-192 (Nucletron) was employed. Hyperthermia was administered to patients using aradiofrequency system with an endotract electrodes. A new endotract applicator, which a 6Fr. Radiation sourse tube was able to be inserted was used totreat for esophagial cancer. During intraluminal heat treatment of 30 min., brachytherapy was performed at a dose of 3.0-4.0Gy in fraction, and this treatment was performed 2 times/2 weeks. Intra cavitary thermoradiation therapy for esophageal canceris effective treatment. However, in patients who have been treated with intracavitary brachytherapy during heat treatment, this combination was not been getermined, the reasonable radiation dose, when is treated with intraluminal radiation therapy during hyperthemia, has to determine.
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