| Budget Amount *help |
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1996: ¥200,000 (Direct Cost: ¥200,000)
Fiscal Year 1995: ¥1,900,000 (Direct Cost: ¥1,900,000)
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| Research Abstract |
1.To examine the reliability and usefulness of a video-based Hirschberg test under clinical conditions, we estimated eye deviation in 87 patient with strabismus through automated analysis of corneal reflex displacement. The repetability of measurement, the comparison with the PACT,and the distribution of the Hirschberg ratio were studied. The 95% limits of agreement of the video-based Hirschberg test evaluated by repeated measurements were (]SY.+-。[)0.18mm ((]SY.+-。[)2.2ﾟ) for the horizontal deviation and (]SY.+-。[)0.28mm ((]SY.+-。[)3.4ﾟ) for the vertical deviation. The 95% limits of agreement betweenthe Hirschberg measures and the PACT were within (]SY.+-。[)7.8ﾟ. The average ((]SY.+-。[)SD) Hirschberg ratio was 12.3(]SY.+-。[)1.2ﾟ/mm. The video-enhanced Hirschberg test shows good repeatability and ease of application, even in the testing infants. In quantitative analysis, however, systematic error from intersubject variance of the Hirschberg ratio should be taken into account.
2.To evaluate the usefulness of newly developped measurement of strabismic deviations based on the entrance pupil ellipticity, we estimate simulated eye deviation in 8 normal subjects with this technique, and analyzed measurement error. Strabismic deviation (rheta) and its measurement (phi) were highly correlated (r=0.86, p<0.001). A linear regression function (phi=0.71rheta+4.39) was obtaied ; its MRS error was 5.6 degrees. This technique has the advantage of providing sys deviation without any scale factor. However note should be taken of possible measurement error deriving from refractive distortion of the pupillary image, and random measurement error from inadequate threshold level.
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