| Project/Area Number |
07671967
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Morphological basic dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
NAGASE Yoshitaka Osaka University, Faculty of Dentistry, Research Associate, 歯学部, 助手 (50252698)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAGAWA Shinji Osaka University, Faculty of Dentistry, Research Associate, 歯学部, 助手 (20263296)
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| Project Period (FY) |
1995 – 1996
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| Project Status |
Completed (Fiscal Year 1996)
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| Budget Amount *help |
¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 1996: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1995: ¥1,400,000 (Direct Cost: ¥1,400,000)
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| Keywords | hypoglossal nerve / motoneuron / intracellular recording / intracellular staining / horseradish peroxidase / Neurolucida |
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| Research Abstract |
The morphology and physiology of hypoglossal motoneurons were studied by the methods of intracellular recording and staining with horseradish peroxidase). The morphological parameters of protruder and retractor hypoglossal motoneurons, which were analuzed three dimensionally with Neurolucida, were not significantly different. The surface areas of their cell bodies were distributed between 1200 and 1600 mum^2. The mean number of stem dendrites was seven and the dendrites were distributed within 1200mum from the center of the soma. As is the case with masticatory motoneurons, some dendrites extended radically in all directions and others not. However, the dendritic morphology of those motoneurons was greatly different from that of masticatory motoneurons. Various postsynaptic potentials were recorded in hypoglossal motoneurons, following the stimulation of masseter and infraalveolar nerves. It suggests that tongue movement should be closely related with mastication. We are now studying the computer simulation of mastication. All the morphological and physiological data in this study will be applied to the simulation and will be of great help to solve the problems of masticatory neuronal circuits.
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