| Project/Area Number |
07807133
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Juntendo University |
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Principal Investigator |
YANAI Akira Juntendo University, Plastic Surg.Professor, 医学部, 教授 (80114495)
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| Co-Investigator(Kenkyū-buntansha) |
INOUE Masahiro Juntendo University, Plastic Surg.Assistant Doctor, 医学部, 助手 (90232561)
ARAI Hajime Juntendo University, Neurosurgery, Associate Professor, 医学部, 助教授 (70167229)
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| Project Period (FY) |
1995 – 1996
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| Project Status |
Completed (Fiscal Year 1996)
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| Budget Amount *help |
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1996: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1995: ¥1,200,000 (Direct Cost: ¥1,200,000)
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| Keywords | next graft / facial palsy / hypoglossal nerve / muscle atrophy / 筋肉萎縮 / 神経変性 |
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| Research Abstract |
At first, twenty dogs were used ot investigate the atrophy of lattisimus Doris muscle after the resection of the motor nerve (thoracodorsal nerve). However the motor nerve was consistedn of multiple funiculi, the hemithoracodorsal procedure of one funiculus was not possible. The atrophy of the muscle was not also found after the longitudinal dissection of the nerve.
Therefore, at the next stage, other twenty dogs' hypoglossal nerves was used as the materials. Hemihypoglossal-facial nerve anastomosis (anastomosis of a split hypoglossal nerve to the facial nerve) were done. Postoperative recovery of facial movement was better in most of the cases than that of the control groups., and the atrophy of the tongue muscle also less than the control groups. Nerve graft at the defect after thehypoglossal nerve traspositon was cleared up and therefore, the nerve graft at the portion was also done in clinical cases and got a good results.
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