| Project/Area Number |
08044052
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| Research Category |
Grant-in-Aid for international Scientific Research
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| Allocation Type | Single-year Grants |
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| Section | Joint Research |
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| Research Institution | TOHOKU UNIVERSITY |
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Principal Investigator |
OGURA Kyozo Tohoku, Univ., Institute for Chemical Reaction Science professor, 反応化学研究所, 教授 (80006303)
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| Co-Investigator(Kenkyū-buntansha) |
LENNARZ W.J State Univ.of New York, Department of Biochemistry and Cell Biology Professor, 生化学及び細胞生物化学科, 教授
SHIDOGI Yoshihiro Gifu Univ.School of Medicine, First Department of Internal Medicine Research Ass, 医学部, 助手 (00111518)
TANAKA Yasuyuki Tokyo Univ.of Agricultuer and Technology, Faculty of Technology professor, 工学部, 教授 (80015114)
KOYAMA Tanetoshi Tohoku, Univ., Department of Biochemistry and Engineering Associate Professor, 助教授 (20089808)
SAGAMI Hiroshi Tohoku, Univ., Institute for Chemical Reaction Science Associate Professor, 反応化学研究所, 助教授 (10134058)
EDWARDS P.A. カリフォルニア大学ロサンゼルス校(UCLA), 生物化学科, 教授
PRESTWICH G. ユタ大学, 医化学科, 教授
POULTER C.D. ユタ大学, 理学部, 教授
ALLEN C.M. フロリダ大学, 生化学及び分子生物化学科, 教授
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| Project Period (FY) |
1996
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| Project Status |
Completed (Fiscal Year 1996)
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| Budget Amount *help |
¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 1996: ¥1,800,000 (Direct Cost: ¥1,800,000)
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| Keywords | prenyltransferase / affinity labeling / isoprenoid / geranylgeranoicacid / dolichol / polyprenol / natural rubber |
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| Research Abstract |
In order to promote and stimulate the mechanistic studies of enzymes involved in the biosynthesis of physiologically important isoprenoids, we invited five eminent American researchers working actively in this field to exchange information with them. Based on the result of discussion, three pieces of joint-research have been started as follows :
1) Studies on the active center of prenyltransferase by means of photoaffinity labeling Collaborator : G.D.Prestwich (Utah University)
2) Studies on the geranylgeranoate receptor Collabortor : Y.Shidoji (Gifu University)
3) Studies on enzymens involved in the biosynthesis of natural rubber Collaborator : Y.Tanaka (Tokyo University of Agriculture and Technology)
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