| Project/Area Number |
08044321
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| Research Category |
Grant-in-Aid for international Scientific Research
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| Allocation Type | Single-year Grants |
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| Section | Joint Research |
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| Research Institution | Juntendo University School of Medicine |
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Principal Investigator |
OKUMURA Ko Prof.Faculty of Medicine Juntendo University, 医学部, 教授 (50009700)
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| Co-Investigator(Kenkyū-buntansha) |
SUGAMURA Kazuo Prof.Faculty of Medicine Tohoku University, 医学部, 教授 (20117360)
TAKATSU Kiyoshi Prof.Faculty of Medicine Tokyo University, 医科学研究所, 教授 (10107055)
HONJO Tasuku Prof.Faculty of Medicine Kyoto University, 医学部, 教授 (80090504)
SASAZUKI Takehiko Prof.Medical of Bioregulation Kyushu University, 生体防御医学研究所, 教授 (50014121)
KISHIMOTO Tadamitsu Prof.Faculty of Medicine Osaka University, 医学部, 教授 (10093402)
VAN Snick J. ルードヴィヒ研究所, 教授
MITCHISON N. ドイツ国立リウマチ研究所, 所長
BORNKAMM G.W 臨床分子研究所, 教授
CHEIN K.R. サンディエゴ大学, 教授
HERZENBERG L スタンフォード大学, 教授
白井 俊一 順天堂大学, 医学部, 教授 (30115860)
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| Project Period (FY) |
1996
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| Project Status |
Completed (Fiscal Year 1996)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,900,000)
Fiscal Year 1996: ¥3,900,000 (Direct Cost: ¥3,900,000)
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| Keywords | MHC / cytokine / signal transduction / CD40, CD40L / CD80, CD86 / HSI / CD95L / IL-6 |
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| Research Abstract |
To exchange the information for the collaborative research between U.S.and Japanese molecular scientists, the symposium inviting scientists from both country was organized. Following are the main item discussed at the meeting for the study of immune regulation and the mechanisms of cell transduction associated to cytokine receptors as well as lymphocyte functioning molecules.
1) The role of MHC in immune respones, especialy for early T cell differentiation.
2) The functional role of cytokine (IL-6 etc) and their receptors (PBSF/SDF-1) in immune response.
3) Involvement of lymphocyte functioning molecules (CD40, CD40L,CD95, CD95L,CD80, CD86) in normal as well as abnormal immune response.
4) Molecular and functional analysis of signal transduction associated molecules such as HSI TRAF,Jak, Src, Stats etc.families.
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