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STUDIES ON THE DlAGNOSIS, PREVENTION AND CONTROL OF EMERGING INFECTIOUS DISEASES IN LABORATORY ANIMALS

Research Project

Project/Area Number 08308041
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Laboratory animal science
Research InstitutionKEIO UNIVERSITY

Principal Investigator

MAEJIMA Kazuyoshi  KEIO UNIVERSITY SCHOOL OF MEDICINE PROFESSOR, 医学部, 教授 (70051464)

Co-Investigator(Kenkyū-buntansha) SATOH Hiroshi  NAGASAKI UNIVERSITY SCHOOL OF MEDICINE ASSOC. PROF., 医学部, 助教授 (50072947)
ARIKAWA Jiro  HOKKAIDO UNIVERSITY SCHOOL OF MEDICINE PROFESSOR, 医学部, 教授 (10142704)
ISHIHARA Chiaki  RAKUNOU-GAKUEN UNIVERSITY PROFESSOR, 獣医学部, 教授 (90082172)
SHIBAHARA Toshiyuki  TOTTORI UNIVERSITY SCHOOL OF MEDICINE ASSOC. PROF., 医学部, 助教授 (70116937)
URANO Toru  KUMAMOTO UNIVERSITY PROFESSOR, 動物資源研究センター, 教授 (90101899)
毛利 資郎  九州大学, 医学部, 教授 (40117271)
Project Period (FY) 1996 – 1998
Project Status Completed (Fiscal Year 1998)
Budget Amount *help
¥14,900,000 (Direct Cost: ¥14,900,000)
Fiscal Year 1998: ¥4,700,000 (Direct Cost: ¥4,700,000)
Fiscal Year 1997: ¥5,000,000 (Direct Cost: ¥5,000,000)
Fiscal Year 1996: ¥5,200,000 (Direct Cost: ¥5,200,000)
KeywordsLaboratory animals / Emerging infections / Diagnosis / Disease control / Virology / Bacteriology / Mycology / Parasitology / 疫学的調査
Research Abstract

In order to detect rapidly and control exactly the emerging / re-emerging infectious diseases in laboratory animals and persons such as animal technicians and researchers, a practical manual "Practical Manual : Diagnosis, Prevention and Control of Emerging / Re-emerging Infectious Diseases in Laboratory Animals" were written. The contents are as follows :
GENERAL INTRODUCTION
PART 1 DIAGNOSIS THERAPY AND PREVERNTION ィイD1*ィエD1
CHAPTER 1 VIRAL DISEASES
CHAPTER 2 BACTERIAL DISEASES
(INCLUDING MYCOPLASMA, RICKETTSIA AND CLAMYDIA INFECTIONS)
CHAPTER 3 MYCOSES
CHAPTER 4 PARASITOSIS
(INCLUDING PROTOZOA AND EXOPARASITE INFECTIONS)
ィイD1*ィエD1 : Mice/Rats/Hamsters/Guineapigs/Rabbits/Dogs/Cats/Pigs/Non-human primates
PART 2 GUIDE FOR CONTROL OF INFECTIONS IN LABORATORY ANIMAL FACILITIES
CHAPTER 1 GENERAL PROCEDURES
CHAPTER 2 INFECTION CONTROL IN ANIMAL EXPERIMENTATION AREAS
CHAPTER 3 SPECIAL PROCEDURES FOR EMERGIN/RE-EMERGING INFECTIOUS DISEASES
PART 3 REFERENCES, TEXTS AND INDEX
The manual will be published by Adthree Co. till October 1, 1999.

Report

(4 results)
  • 1998 Annual Research Report   Final Research Report Summary
  • 1997 Annual Research Report
  • 1996 Annual Research Report
  • Research Products

    (39 results)

All Other

All Publications (39 results)

  • [Publications] YOSHIMATSU, K, et al.: "Hantavirus infectin in SCID mice"J, Vel. Ned. Sci.. 59(10). 803-868 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] ISHIHARA, C. et al.: "C.guilliermondii infection in SCID mice in association with acceleration of"Exp. Anim.. 47(1). 69-73 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] ITOH, Y. et al.: "Rabies virus M protein expressed in E. cole and its regulatory role in"Arch. Virolo.. 141. 671-683 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] OHSAWA, K. et al.: "Replication of rat coronaviruses in intestinal cell line, RCN-9, derived"Exp. Anim.. 45(4). 389-393 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] SHIROTA, O. et al.: "Structure elucidation of trichotetronines"J.Chem. Soc. Perkin. Trans.. 1. 2961-2964 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] OHSHIMA, T. et al.: "Induction of adoptosis in vivo and in vitro by H-1 parvovirus infection"J. Gen. Virol. 79. 3067-3071 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] KITA, M. et al.: "Determination of interferon α 2 allele composition in the genomic DNA from"Japan. J. Interferon Cytokine Res.. 17. 135-140 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] YOSHIMATSU, K. et al.: "Hantavirus infect ion in SCID mice"J. Vet. Med. Sci. 59 (10). 863-868 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] MORII, M. et al.: "Antigenie characterization of Hantaan and Seoul virus nucleocapsid proteins expressed by recombinant Baculovirus : Application of a truncated protein, lacking an antigenic reg ion common to the two viruses, as a serotyping antigen"J. Clin. Microbiol. 36 (9). 2514-2521 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] ISHIHARA. C. et al.: "C. guilliermondii infection in SCID mice in association with acceleration of the elimination of transfused human red blood cells"Exp. Anim. 47 (1). 69-73 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] HAGIWARA. K. et al.: "Demonstration of Borna virus (BVD) in speci fic regions of the brain from horses positive for serum antibodies to BVD but negative for BVD RNA in the blood arid internal organs"Med. Microbiol. Immunol. 186 (1). 19-24 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] ITOH, Y. et al.: "Rabies virus M protein expressed in E. coli and its regulatory role in virion associated transcriptase activity"Arch. Virolo. 141. 671-683 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] OHSAWA, K. et al.: "Replication of rat coronaviruses in intestinal cell line, RCN-9, derived from F344 rats"Exp. Anim. 45 (4). 389-393 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] SHIROTA, O. et al.: "Structure elucidation of trichotetro nines"J. Chem. Soc. Perkin. Trans. 1. 2961-2964 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] OHSHIMA, T. et al.: "Induction of adoptosis in vivo and in vitro by H-1 parvovirus infection"J. Gen. Virol. 79. 3067-3071 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] KITA, M. et al.: "Determination of interferon α2 allele composition in the genomic DNA from healthy volunteers and leukemic patients in Japan"Japan. J. Interferon Cytokine Res. 17. 135-140 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] FUJINO, T. et al.: "The expulsion of Echinostoma trivoluis : worm kinetics and intestinal reactions in C3H/HeN mice treated with dexamethasone"J. Helminthol. 71. 257-259 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] KAWAMOTO, E. et al.: "Evaluation of transport media for Pasteurella miltocida isolates from rabbit nasal specimens"J. Clin. Microbiol. 35 8). 1948-1951 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] UENO, V. et al.: "Prevalence of "Orphan" parvovurus infections in mice arid rats"Exp. Anim. 47 (3). 207-210 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] OHSUGI, T. et al.: "HTLV-I infections in offspring derived from HTLV-I carrier rats during the suckling period"Kurume Med. J.. 43 (1). 1-9 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] YOSHIMATSU,K.et al.: "Hantavirus infection in SCID mice." J.Vet.Med.Sci.59(10). 863-868 (1997)

    • Related Report
      1998 Annual Research Report
  • [Publications] ISHIHARA,C.et al.: "C.guilliermondii infection in SCID mice in association with acceleration." Exp.Anim.47(1). 69-73 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] ITOH,Y.et al.: "Rabies virus M protein expressed in E.coli and its regulatory role." Arch.Virolo.141. 671-683 (1996)

    • Related Report
      1998 Annual Research Report
  • [Publications] OHSAWA,K.et al.: "Replication of rat coronaviruses in intestinal cell line,RCN-9,derived" Exp.Anim.45(4). 389-393 (1996)

    • Related Report
      1998 Annual Research Report
  • [Publications] SHIROTA,O.et al.: "Structure elucidation of trichotetronines." J.Chem.Soc.Perkin.Trans.1. 2961-2964 (1997)

    • Related Report
      1998 Annual Research Report
  • [Publications] OHSHIMA,T.et al.: "Induction of adoptosis in vivo and in vitro by H-1 parvovirus infection." J.Gen.Virol.79. 3067-3071 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] KITA,M.et al.: "Determination of interferon-α 2 allele composition in the genomic DNA." Japan.J.Interferon Cytokine Res.17. 135-140 (1997)

    • Related Report
      1998 Annual Research Report
  • [Publications] 鈴木照雄・他: "南米スリナム産リスザルの検疫" 実験動物技術. 32(2). 155-158 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] KAWAMOTO,E.et al.: "Evaluation of transport media for Pasteurella multocida from rabbit specimens" Journal of Clinical Microbiology. 35(8). 1948-1951 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 野口和浩・他: "動物実験施設内でのゴキブリの発生状況" 実験動物技術. 32(2). 147-154 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] ISHIHARA,C.et al.: "Candida guilliermondii infrction in SCID mice" Experimental Animals. 47(1). 69-73 (1998)

    • Related Report
      1997 Annual Research Report
  • [Publications] 吉川康弘・他: "サル類を媒介する人獣共通感染症の予防に関する研究" (厚生省科学研究費:厚生行政科学研究事業報告書-平成8年度-), 127 (1998)

    • Related Report
      1997 Annual Research Report
  • [Publications] 有川二郎・他: "腎症候性出血熱ウイルス感染の血清診断法と検査システムの確立" (文部省科学研究費:研究成果報告書-平成6〜8年度-), 66 (1998)

    • Related Report
      1997 Annual Research Report
  • [Publications] 前島一淑・他: "最新実験動物学" 朝倉書店, 174 (1998)

    • Related Report
      1997 Annual Research Report
  • [Publications] 有川二郎: "ハンタウイルス感染症" 科学. 67 (2). 139-142 (1997)

    • Related Report
      1996 Annual Research Report
  • [Publications] 吉川泰弘: "輸入野性動物と人獣共通感染病" 科学. 67 (2). 157-164 (1997)

    • Related Report
      1996 Annual Research Report
  • [Publications] TERAMOTO,K.et al.: "Changes in body weight and organ weight of Ishibashi (IS) rats with growth" Experimental Animals. 45 (4). 317-323 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 浦野徹・他: "実験動物技術体系" (有)アドスリ-, 675 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 前島一淑・他: "動物の処分方法に関する指針の解説" (社)日本獣医師会, 68 (1996)

    • Related Report
      1996 Annual Research Report

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Published: 1996-04-01   Modified: 2016-04-21  

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