| Project/Area Number |
08457353
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | Tokyo Women's Medical College. |
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Principal Investigator |
IMAI Yasuharu Tokyo Women's Medical College, Faculty of Medicine, Professor, 医学部, 教授 (30075246)
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| Co-Investigator(Kenkyū-buntansha) |
BEPPU Toshiyuki Tokyo Women's Medical College, Faculty of Medicine, Researchi Fellow, 医学部, 助手 (30181481)
SEO Kazuhiro Tokyo Women's Medical College, Faculty of Medicine, Assistant Professor, 医学部, 講師 (20167472)
HOSHINO Shuichi Tokyo Women's Medical College, Faculty of Medicine, Assistant Professor, 医学部, 講師 (80120046)
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| Project Period (FY) |
1996 – 1997
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| Project Status |
Completed (Fiscal Year 1997)
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| Budget Amount *help |
¥4,500,000 (Direct Cost: ¥4,500,000)
Fiscal Year 1997: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 1996: ¥3,400,000 (Direct Cost: ¥3,400,000)
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| Keywords | Cardiopulmonary bypass / Assisted circulation / Centrifugal pump / Computer control / Microcomputer / Automatic control |
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| Research Abstract |
A control system for assisted circulation was developed utilizing a microcomputer. The control system, consisting of a microcomputer, a centrifugal pump, a venous tube occluder, and a level sensor for a reservoir, regulates both arterial infusion and venous withdrawal flow throughout assisted circulation. The computer monitors central venous pressure, left atrium pressure, aortic pressure, and the amount of blood in the reservoir and controls the rotational speed of the pump and the degree of opening of the tube occluder with a control interval of one second. The computer keeps the infusion flow rate within a predetermined range and regulates left atrium pressure to a set point in order to maintain aortic pressure. We designed an online screening algorithm to prevent artifacts on pressure measurements from changing the flow rates. The computerized controller was applied on two patients with low output syndrome after the open-heart surgery and regulated the flow rate and left atrium pressure for four days.
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