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Pathophysiological Study on Phonatory Function after Phonosurgery

Research Project

Project/Area Number 08457449
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Otorhinolaryngology
Research InstitutionThe University of Tokyo

Principal Investigator

NIIMI Seiji  Univ.of Tokyo, Grad.School Med., Professor, 大学院・医学系研究科, 教授 (00010273)

Co-Investigator(Kenkyū-buntansha) KIMADA Masanobu  Haskins Lab., Researcher, 生理学第一講座, 助手
TAYAMA Nirou  Univ.of Tokyo, Med.Hospital, Lecturer, 医学部・附属病院, 講師 (50221403)
MORI Koichi  Univ.of Tokyo, Grad.School Med., Research Associate, 大学院・医学系研究科, 助手 (60157857)
Project Period (FY) 1996 – 1997
Project Status Completed (Fiscal Year 1997)
Budget Amount *help
¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 1997: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1996: ¥2,800,000 (Direct Cost: ¥2,800,000)
KeywordsHigh speed digital imaging system / Partial laryngectomy / Vocal fold vibration / Spasmodic dysphonia / Dysphagia / Dysphonia in children / 小児の音声言語障害 / 声帯振動 / 音声障害 / 音声外科 / 二重声 / 嚥下 / 声門下圧
Research Abstract

In this project, the high speed digital imaging system has been developed and can be used to evaluate the vocal folds function of the patient. The sound source of the partial laryngectomized patient was investigated to find that the ary-epiglottic fold can vibrate to generate the voice. This finding gives us a new idea to improve the voice quality to the post operative patient.
By using the high speed digital imaging system, some causative factors of the voice disorders have been clarified. Especially, the mode of the onset of the phonation has an effect not only at the beginning of the phonation but at the following stationary phonation. It means that the voice attack should be one of the most important factor for the vocal hyginene. This also provides the new knowledge to make a clinical program of the rehabilitation after phonosurgery.
Recently, the number of the patients with functional dysphonia tends to be increasing especially, among the professional voice users. Spasmodic dysphonia is one of the functional dysphonia which is difficult to treat. We have been using the botulinum toxin. Vocal fold vibration, psychoacoustic impression and acoustic parameters were evaluated pre and post treatment. The neurological back ground as an etiologic factor was strongly suggested.
Swallowing function after phonosurgery was also evaluated. It becomes clear that the phonatory function and the swallowing function improves together.
Voice and speech disorders in the children are important from educational point of view as well as medical point of view. We have started a pilot study to find out the evaluation system for the voice and speech disorders in children.

Report

(3 results)
  • 1997 Annual Research Report   Final Research Report Summary
  • 1996 Annual Research Report
  • Research Products

    (37 results)

All Other

All Publications (37 results)

  • [Publications] 新美 成二: "喉頭の筋電図検査" JOHNS. 13・5. 795-799 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 阿部 雅子: "側音化構音の構音動態の観察-超音波断層法による観察-" 音声言語医学. 39・1. 9-15 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] K.Tunoda: "Laryngeal adjustment in whispering." Annals Otd.Rhirol.Luryngol.106・1. 41-43 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] K.Mori: "Across-frequency nonlineur in hibition by GABA in processing of interaural time difference" Hearing Research.111・2. 22-30 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] S.Imaizumi: "Vocal identification of speaker and emotion activates different brain regions." Neuro Report. 8・12. 2809-2812 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 熊田 政信: "痙攣性発声障害の新らしい評価法:モ-ラ法" 音声言語医学. 38・2. 176-181 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Seiji Niimi: "Electromyographic examination of the larynx." JOHNS. 13 (5). 759-799 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Seiji Niimi: "Care for children with voice and speech disorders." Clinical pediatrics. 49. 1579-1585 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Hideto Saigusa et al: "A new artificial pharynx for patients with severe dysphagia" J.Jpn.Bronchoeso [hago]. Soc. 48 (4). 297-302 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Hideto Saigusa et al: "A case of laryngeal granuloma due to angiotensin-converting enzyme inhibitor therapy for heypertension." Larynx. 9 (1). 167-169 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Miyoko Ishige et al: "a case of functional articulationdisorder with tongue retraction as main symptom." Jpn.J.Logopedics and Phoniatrics. 38 (4). 329-336 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Masako Abe et al: "Articulatory movements of lateral articulation." Jpn.J.Logopedics and Phoniatrics. 39 (1). 9-15 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Koichi Tunoda et al: "Laryngeal adjustment in whispering" Annals Otl.Rhinol.Laryngol. 106 (1). 41-43 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Koichi Tunoda et al: "Stroboscopic observation of the larynx after radiation in patients with T1 glottic carcinoma." Adta Otolaryngol.Suppl.527. 165-166 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] K.Mori: "Across-frequency nonlinear inhibition by GABA in processing of interaural time difference." Hearing Res.111 (2). 22-30 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Satoshi Imaizumi et al: "Vocal identification of speaker and emotion activates differerent brain regions." NeuroReport. 8 (12). 2809-2812 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Masanobu Kumada et al: ""More method" for objective evaluation of severity of spasmodic dysphonia." Jpn.J.Logopedics and Phoniatrics. 38 (2). 176-181 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 新美 成二: "喉頭の筋電図検査" JOHNS. 13・5. 795-799 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 新美 成二: "言語障害児の保健管理" 小児科臨床. 49・増. 1579-1585 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 新美 成二: "学校保健における音声言語障害" JOHNS. 13・1. 125-130 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 三枝 英人: "咽喉咽頭作成の試み-重度嚥下障害の筋緊張性ジストロフィー症例に対して" 日気食会報. 48・4. 297-302 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 三枝 英人: "アンギオテンシン変換酵素阻害剤の副作用である咳嗽が誘因であると考えられた喉頭肉芽種の一例" 喉頭. 9・1. 167-169 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 石毛 美代子: "舌後退を主症状とした機能性構音障害の一例" 音声言語医学. 38・4. 329-336 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 阿部 雅子: "側音化構音の構音動態の観察-超音波断層法による観察-" 音声言語医学. 39・1. 9-15 (1998)

    • Related Report
      1997 Annual Research Report
  • [Publications] K.Tunoda: "Laryngeal adjustment in whispering" Arnals Otd.Rhinol.Laryngol.106・1. 41-43 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] K.Tunoda: "Stroboscopic observation of the larynx after radiation in patients with T1 glottic carcinoma" Acta Otolaryngol.Suppl.527. 165-166 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] K.Mori: "Across-frequency nonlinear inhibition by GABA in processing of interaural time difference" Hearing Research. 111・2. 22-30 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] S.Imaizumi: "Vocal identification of speaker and emotion activates different brain regions" Neuro Report. 8・12. 2809-2812 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] S.Imaizumi: "Observation of neural processes of auditory scene analysis by magnetoencepha lography" Acta Otolaryngol Suppl.532. 106-108 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 熊田 政信: "痙攣性発声障害の新しい評価法:モ-ラ法" 音声言語医学. 38・2. 176-181 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 熊田 政信: "痙攣性発声障害の多彩な症状を統一的に説明する2つの仮説" 医学のあゆみ. 183・8. 492-496 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] K.Tsunoda: "Laryngeal adjustment in whispering,MRI study" Ann.Otol Rhinol Laryngol. 106・1. 41-43 (1997)

    • Related Report
      1996 Annual Research Report
  • [Publications] 今泉 敏: "声の変動特性-音響分析による評価-" 喉頭. 8・2. 116-122 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 三枝 英人: "前方型披裂軟骨脱臼症の治療経験" 日本気管食道科学会会報. 47・6. 539-544 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 新美 成二: "咽頭弁形成術" 耳鼻咽喉科・頭頸部外科. 68・11. 88-92 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 宮地 麻美子: "沈着性病変の声帯にみられた特異な振動パターン" 音声言語医学. 37・2. 223-227 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 新美 成二: "学校保健における音声言語障害" JOHNS. 13・1. 125-130 (1997)

    • Related Report
      1996 Annual Research Report

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Published: 1996-04-01   Modified: 2016-04-21  

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