| Project/Area Number |
08457529
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
補綴理工系歯学
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| Research Institution | HIROSHIMA UNIVERSITY |
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Principal Investigator |
SATO Yuuji Hiroshima Univ., Sch.of Dentistry, Asociate Professor, 歯学部, 助教授 (70187251)
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| Co-Investigator(Kenkyū-buntansha) |
YAMAKI Masao Hiroshima Univ., Sch.of Dentistry, Professor, 歯学部, 教授 (00034166)
YOSHIDA Mitsuyoshi Hiroshima Univ., Sch.of Dentistry, Research Assistant, 歯学部, 助手 (50284211)
ABE Yasuhiko Hiroshima Univ., Sch.of Dentistry, Research Assistant, 歯学部, 助手 (00253097)
TSUGA Kazuhiro Hiroshima Univ., Sch.of Dentistry, Assistant Professor, 歯学部・附属病院, 講師 (60217289)
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| Project Period (FY) |
1996
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| Project Status |
Completed (Fiscal Year 1996)
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| Budget Amount *help |
¥4,400,000 (Direct Cost: ¥4,400,000)
Fiscal Year 1996: ¥4,400,000 (Direct Cost: ¥4,400,000)
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| Keywords | antimicrobial effect / denture base materials / tissue conditioner / silver-zeolite / Ag^+ |
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| Research Abstract |
The purpose of the first study was to elucidate the in vitro antimicrobial effect of five commercially available tissue conditioners containing silverzeolite (2 wt%) on Candida albicans and nosocomial respiratory infectioncausing bacteria, Staphylooccus aureus and Pseudomonas aeruginosa. Tissue conditioners containing silver-zeolite have been shown to have antimicrobial effects for 4 weeks on C.albicans and nosocomial respiratory infection-causing bacteria in saliva in vitro.
The purpose of the second study was to clarify the concentration of Ag^+ released into distillled water and artificial saliva from both only silverzeolite and tissue conditioner containing silver-zeolite (2 wt%) at 37ﾟC for 24 hours. The results indicate that the antimicrobial effect of tissue conditioner containing silver-zeolite may be closely related to Ag^+ on the surface of it because of an extremely small quantity of Ag^+ released into each solution.
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