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Study on Hyper Thermal Neutron Irradiation Field for Neutron Capture Therapy

Research Project

Project/Area Number 08458125
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field エネルギー学一般・原子力学
Research InstitutionKYOTO UNIVERSITY

Principal Investigator

KOBAYASHI Tooru  Kyoto University, Research Reactor Institute, Associate Professor, 原子炉実験所, 助教授 (90089136)

Co-Investigator(Kenkyū-buntansha) SAKURAI Yoshinori  Kyoto University, Research Reactor Institute, Research Associate, 原子炉実験所, 助手 (20273534)
Project Period (FY) 1996 – 1997
Project Status Completed (Fiscal Year 1997)
Budget Amount *help
¥7,100,000 (Direct Cost: ¥7,100,000)
Fiscal Year 1997: ¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 1996: ¥3,900,000 (Direct Cost: ¥3,900,000)
KeywordsNeutron Capture Therapy / Hyper Thermal Neutron / High Temperature Scatterer / Graphite / Beryllium / Zirconium Hydride / 中性子捕捉療法
Research Abstract

The purpose of this research is to clarify the irradiation characteristics of hyper-thermal neutrons for a living body, and the feasibility of hyper thermal neutron irradiation field, by experiments and simulation calculations.
In 1996 (Heisei 8), a "test-type" hyper-thermal neutron generator was designed from the results of the basic researches mainly with simulation calculations, and the "high-temperature scatterer" part was assembled. The design goal of this generator was that the attainable maximum temperature was almost 1200 degrees centigrade (1500K). From the standing-point of safety first at high-temperature experiments, stainless steal, which has good characteristics of heat-proof and corrosion-proof, was selected as main material of the structural frame. The electric heating using molybdenum high-temperature heaters, the heat remove by molybdenum heat reflectors, and the heat measurement by R-type thermo-couples were applied. Graphite scatterer was selected because of its stab … More ility at high temperature. The scatterer is possible to be replaced with the other scatterer.
In 1997 (Heisei 9), the "controller" part was made and combined with the high-temperature scatterer part, and finally, the generator was completed. Before the employment of the generator at neutron irradiation field, the heating tests were performed. From the test results, it was confirmed that the scatterer maximum temperature was attainable to be 1200 degrees centigrade, and that there was no problem for thermal stability, thermal controllability and safety at the high temperature employment. As one of the experiments for the characteristics estimation, the neutron energy spectrum dependent on the scatterer temperature was estimated by TOF (time of flight) method using the LINAC (Electron Linear Accelerator) neutron generator at KURRI (Kyoto University Research Reactor Insitute). The estimation by simulation calculations were also performed. From the experiment and calculation results, it was confirmed that the neutron temperature shifted to be higher according to the scatterer temperature.
At present, phantom experiment at the KUR (Kyoto University Reactor) Heavy Water Facility are planning in order to estimate the neutron dose distribution in a living body, on the assumption of the application of hyper-thermal neutrons irradiation to actual NCT. Less

Report

(3 results)
  • 1997 Annual Research Report   Final Research Report Summary
  • 1996 Annual Research Report

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Published: 1996-04-01   Modified: 2016-04-21  

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