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STUDY ON REAL-TIME MEASUREMENT OF CARDIAC MUSCLE VISCOELASTICITY USING AN ULTRASONIC TACTILE MICROSENSOR CATHETER

Research Project

Project/Area Number 08458296
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionNATIONAL CARDIOVASCULAR CENTER RESEARCH INSTITUTE

Principal Investigator

TSUJI Takayuki  NATIONAL CARDIOVASCULAR CENTER RESEARCH INSTITUTE,DEPARTMENT, DIRECTOR, 実験治療開発部, 部長 (00075764)

Co-Investigator(Kenkyū-buntansha) OMATA Sadao  NIHON UNIVERSITY FACULTY OF ENGINEERING, PROFESSOR, 工学部, 教授 (90060186)
FUJISATO Toshia  NATIONAL CARDIOVASCULAR CENTER RESEARCH INSTITUTE, RESEARCHER, 実験治療開発部, 室員 (60270732)
MIYAWAKI Fujio  NATIONAL CARDIOVASCULAR CENTER RESEARCH INSTITUTE, CHIEF RESEARCHER, 実験治療開発部, 室長 (50174222)
後藤 葉一  国立循環器病センター, 心臓内科, 医長 (40142179)
Project Period (FY) 1996 – 1998
Project Status Completed (Fiscal Year 1998)
Budget Amount *help
¥7,500,000 (Direct Cost: ¥7,500,000)
Fiscal Year 1998: ¥1,600,000 (Direct Cost: ¥1,600,000)
Fiscal Year 1997: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1996: ¥4,500,000 (Direct Cost: ¥4,500,000)
Keywordsultrasonic tactile sensor / resonant frequency shift / microtip catheter / viscoelasticity / beating heart muscle / in vivo organ viscoelasticity
Research Abstract

Aim of the project is to develop a tactile sensor catheter having 1.5 mm in diameter equipped with the 200 kHz ultrasonic microtip that can detect in real-time viscoelasticity change of beating heart muscle. Influence of contact pressure of the tip on the objects which are silicone rubber discs having various silicone contents from 40 to"90 % was studied by varying tip weight loaded with various sizes of lead chips from 5 to 100 g. Ultrasonic resonant frequency shift (DELTAf) depended on the tip load. Five gram load was decided appropriate for measuring soft tissues.
The negative DELTAf became bigger in softer material. Viscoelasticity measurements of in vivo organs including liver, kidney, spleen and muscles in anesthetized dogs revealed the DELTAf of muscle was smaller than other tissues. Skeletal muscle, kidney, liver and spleen were softer in order. Dynamic changes associated with the left ventricular wall motion was obtained by the catheter inserted via carotid artery However, the signals originating from viscoelasticity changes of the ventricular muscle and from the tip collision against the ventricular wall in systole cannot be discriminated. Improvement of the catheter should be necessary for this purpose.

Report

(4 results)
  • 1998 Annual Research Report   Final Research Report Summary
  • 1997 Annual Research Report
  • 1996 Annual Research Report
  • Research Products

    (19 results)

All Other

All Publications (19 results)

  • [Publications] 村田正典辻 隆之、ほか: "超音波接触センサーによるイヌ 骨格筋虚血のリアルタイム評価" 日本機械学会第9回バイオエンジニアリング学術講演会. 210. 71-71 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Murata M, Tsuji T, et al: "Measurement of stiffness of silicon and in vivo organs with an ultrasonic tactile sensor" Proceedings of 3rd Far-Eastern Symposium on Biomedical Masterials. 103-103 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Murata M, Tsuji T, et al: "Measurement of stiffness of organs in vivo with an ultrasonic tactile sensor" Proceedngs of World Congress on Medical Physics and Biomadical Engineering. 132-132 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] 村田 正典、辻 隆之、ほか: "超音波触覚カテーテルによるイヌ左室壁粘弾性のリアルタイム計測" 第34回日本ME学会. 63. 227-227 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] 村田正典、辻 隆之、ほか: "リモートサージェリのための触覚センサーによるイヌin vivo臓器のリアルタイム評価" 第5回日本コンピュータ外科学会. VIII(5). 109-110 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Murata M, Tsuji T, Haibo R, Omata S.: "Measurement of stiffness of organs in vitro with an ultrasonic tactile sensor" Medical & Biological Engineering & Computing. Vol.35, Supplement Part I. 132 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] 村田正典 辻 隆之、ほか: "超音波触覚センサーによるイヌ骨格筋虚血のリアルタイム評価" 日本機械学会第9回バイオエンジニアリング学術講習会. 210. 71-71 (1997)

    • Related Report
      1998 Annual Research Report
  • [Publications] Murata M,Tsuji T,et al.: "Measurement of stiffness of silicon and in vivo organs with an ultrasonic tactile sensor" Proceedings of 3rd Far-Eastern Symposium on Biomedical Materials. 103-103 (1997)

    • Related Report
      1998 Annual Research Report
  • [Publications] Murata M,Tsuji T,et al.: "Measurement of stiffness of organs in vivo with an ultrasonic tactile sensor" Proceedngs of World Congress on Medical Physics and Biomadical Engineering. 132-132 (1997)

    • Related Report
      1998 Annual Research Report
  • [Publications] 村田 正典、辻 隆之、ほか: "超音波触覚カテーテルによるイヌ左室壁粘弾性のリアルタイム計測" 第34回日本ME学会. 63. 227-227 (1996)

    • Related Report
      1998 Annual Research Report
  • [Publications] 村田正典、辻 隆之、ほか: "リモートサージェリのための触覚センサーによるイヌ in vivo臓器のリアルタイム評価" 第5回日本コンピュータ外科学会. VIII(5). 109-110 (1996)

    • Related Report
      1998 Annual Research Report
  • [Publications] 村田正典、辻隆之、他: "超音波触覚センサーによるイヌin vivo臓器粘弾性のリアルタイム評価" 第20回日本バイオレオロジー学会年会抄録集. 41-41 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 村田正典、辻隆之、他: "超音波触覚センサーによる臓器粘弾性のin vivo計測" 医用電子と生体工学. 35(Suppl). 375-375 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Murata M,Tsuji T,et al: "Measurement of stiffness of silicon and in vivo organs with an ultrasonic tactile sensor" Proceedings of 3rd Far-Eastern Symposium on Biomedical Materials. 103-103 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Murata M,Tsuji T,et al: "Measurement of stiffness of organs in vivo with an ultrasonic tactile sensor" Proceedings of World Congress on Medical Physics and Biomadical Engineering. 132-132 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 村田正典: "超音波触覚カテーテルによるイヌ左室壁粘弾性のリアルタイム計測" 医用電子と生体工学 第35回日本ME学会大会論文集. Vol.34. 227 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 村田正典: "超音波共振カテーテルによるイヌ左室壁粘弾性動的計測" 第19回日本バイオレオロジー学会年会抄録集. 49 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 村田正典: "超音波触覚カテーテルを用いたイヌ左室壁粘弾性のリアルタイム計測 -臨床応用を目指して-" 日本臨床生理学会雑誌 臨時増刊号. Vol.26. 107 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 村田正典: "超音波触覚カテーテルによるイヌ左室壁粘弾性のリアルタイム計測" 第7回バイオエンジニアリング学術講演会・夏季セミナー講演論文集. 96-29. 227 (1996)

    • Related Report
      1996 Annual Research Report

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Published: 1996-04-01   Modified: 2016-04-21  

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