| Project/Area Number |
08555209
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
工業分析化学
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| Research Institution | Hokkaido University |
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Principal Investigator |
SHIMOMURA Masatsugu Hokkaido Univ., Res. Inst. Elect. Scie., Prof., 電子科学研究所, 教授 (10136525)
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| Co-Investigator(Kenkyū-buntansha) |
篠原 悦夫 オリンパス光学工業技術開発本部, 係長(研究職)
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| Project Period (FY) |
1996 – 1997
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| Project Status |
Completed (Fiscal Year 1997)
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| Budget Amount *help |
¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1997: ¥1,000,000 (Direct Cost: ¥1,000,000)
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| Keywords | monolayrs / fluorescence / optical sensor / ion sensor / LB Films / bilayr membranes / polyion complex / nucleic acid / マルチチャンネル |
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| Research Abstract |
In order to design a multi-channel sensing system based on pattern recognition, fluorescence response of bilayr membranes having octadecylrhodamine B to various inorganic anions were investigated. Fourteen cationic amphiphiles, double chain amphiphiles and single chain amphiphiles with a rigid aromatic segment, were used as the sensing bilayr membranes. Fluorescence response of bilayr membranes was strongly depend not only on inorganic anions but also on the chemical structure of the bilayr forming amphiphile. Fluid bilayr membranes were more sensitive than those of gel state. Iodide ion act as a fluorescence quencher of the most bilayr membranes. Carbonate ions specifically enhanced fluorescence intensity of the bilayr membrane of a single chain viologen amphiphile. Based on the results of the bilayr membranes fluorescence responses of Langmuir-Blodgett films of the cationic amphiphiles complexed with counter charged polyelectrolites, Poly(stirenesulfonate), poly(vinylsulfate), and carboxymethyl-cellulose, were investigated. The chemical structure of the counter charged polymer strongly affected the fluorescence response even if the same amphiphile was used as a monolayr forming compound. A large variety of the fluorescence of the molecular films is essential to the molecular design of the multi-channel ion sensors.
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