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Development of integrated system of mental test and brain information analysis for diagnosis as well as treatment evaluation of language and thought disorders

Research Project

Project/Area Number 08558094
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section展開研究
Research Field Biomedical engineering/Biological material science
Research InstitutionUniversity of Tokyo

Principal Investigator

ITOH Kenji  University of Tokyo, Grad School Med, Assist Prof, 大学院・医学系研究科, 助手 (80010106)

Co-Investigator(Kenkyū-buntansha) KOSHIDA Ichiro  Tokyo Engineering Unieversity, Fac Eng, Assoc Prof, 工学部, 助教授 (00192055)
YUMOTO Masato  University of Tokyo, Med Hospital, Assist Prof, 医学部・付属病院, 助手 (30240170)
NAKAGOME Kazuyuki  University of Tokyo, Med Hospital, Assist Prof, 医学部・付属病院, 助手 (30198056)
FUKUDA Masato  University of Tokyo, Med Hospital, Lecturer, 医学部・付属病院, 講師 (20221533)
HIRAMATSU Kenichi  University of Tokyo, Med Hospital, Assist Prof, 医学部・付属病院, 助手 (50218814)
Project Period (FY) 1996 – 1997
Project Status Completed (Fiscal Year 1997)
Budget Amount *help
¥10,000,000 (Direct Cost: ¥10,000,000)
Fiscal Year 1997: ¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 1996: ¥7,500,000 (Direct Cost: ¥7,500,000)
KeywordsTopography / Mental function test / Thought disorder / Brain functional modules / Magnetoencephalography / Fast wave / Language function / Event-related Potentials / トポグラフィ / 言語障害 / 電流源密度 / 脳波
Research Abstract

We investigated and obtained following results on the development of integrated simultaneous acquisition system of test data and brain infomation of language, cognitive and mental functions for diagnosis as well as treatment evaluation of language and thought disorders.
1.We applied the feature extraction and correlation analysis method to brain functional data during language and thought processes in order to clarify the importance of coincident cerebral functional modules localized and associated by fast rhythmic activities.
2.We constructed a on-line task presenting system in order to test mental and language functions by computer-controlled audio-visual presentation.
3.We confirmed the applicability of data-base on mental test on normals and schizophrenics to subjective evaluation of language and thought disorders.
4.We elucidated the necessity of such as structure-function corresponding model between 3D object of brain massive and scalp surface object for final routine integrating test and analysis.
5.We confirmed the priority of network user interface by Java and moving data files by Quick Time 3.0 for interactive manipulation of multiple combined data in picture format.
6.We completed the integrated test and analysis system and examined the system for practical application to conclude that more than 128channel EEG/MEG data are necessary compared to recent high resolution fMRI and also that technique of multiple simultaneous measuring on brain functions should be established.

Report

(3 results)
  • 1997 Annual Research Report   Final Research Report Summary
  • 1996 Annual Research Report
  • Research Products

    (29 results)

All Other

All Publications (29 results)

  • [Publications] Mazuka R.Itoh K.: "Processing down the garden path in Japanese:processing of sentences with lexical homonyms." Journal of Psycholinguistic Research. 26. 207-228 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Itoh K, Koshida I, Hiramatsu K, etal: "Topographic correnation analysis of event-related potentials and oscillations during linguistic and nonlinguistic porocesses" Electroencephalography and Clinical Neurophysiology. 103(S). 98-98 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Koshida I, Itoh K, Hiramatsu K, etal: "A high resolution time domain EEG visualization system for personal computer" Electroencephalography and Clinical Neurophysiology. 103(S). 114-114 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 福田 正人・畑 哲信・丹羽 真一・伊藤 憲治・他: "精神分裂病の思考障害" 電子情報通信学会技術研究報告. TL97-7. 17-29 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 中込 和幸・福田 正人・畑 哲信・伊藤 憲治・他: "精神分裂病におけるNd,MMNのscalp current density mapping の検討" 脳波と筋電図. 25. 195-195 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Itoh K, Nakagome K, Hiramatsu K, Koshida I: "Speech processing and the brain" Proceedings of the Workshop on Thought and Language. 1-8 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 丹羽 真一・鶴 紀子・伊藤 憲治・他: "事象関連電位:事象関連電位と情報科学の発展" 新興医学出版, 205 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Mazuka R,Itoh K,Kondo T: "Processing down the garden path in Japanese : processing of sentences with lexical homonyms" Journal of Psycholinguistic Research. 26. 207-228 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Itoh K,Koshida I,Hiramatsu K,Fukuda M et al: "Topographic correnation analysis of event-related potentials and oscillations during linguistic and nonlinguistic processes" Electroencephalography and Clinical Neuro-physiology. 103 (S). 98 (1977)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Koshida I,Itoh K,Hiramatsu K,Fukuda M,et al: "A high resolution time domain EEG visualization system for personal computer" Electroencephalography and Clinical Neuro-physiology. 103 (S). 114 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Fukuda M,Hata A,Niwa S,Itoh K,et al: "Thought disorders in schizophrenics" IEICE Technical Report. TL97-7. 17-29 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Nakagome K,Fukuda M,Hata A,Itoh K,et al: "Scalp current density mapping of Nd, MMN in schizophrenics" Jpn J EEG & EMG. 25. 195 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Koshida I,Itoh K,Hiramatsu K,Fukuda M,et al: "Evaluation of 2D topographic processing with multichannel EEG measuring system" Jpn J EEG & EMG. 25. 132 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Itoh K,Nakagome K,Hiramatsu K,Koshida I,et al: "Speech processing and the brain" Proceedings of the Workshop on Thought and Language. 1-8 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Niwa S,Tsuru N,Itoh K,et al: Event-Related Potentials and the Development of Information Science. Shiko-Igaku Shuppan-sha, 205 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Itoh K, Koshida I, Hiramatsu K, et al: "Topographic correnation analysis of event-related potentials and osicillations during linguistic and nonlinguistic processes" Electroencephalography and Clinical Neurophysiology. 103(S). 98-98 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Koshida I, Itoh K, Hiramatsu K, et al: "A high resolution time domain EEG visualization system for personal computer" Electroencephalography and Clinical Neurophysiology. 103(S). 114-114 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 中込和幸, 福田正人, 畑哲信, 伊藤憲治, 他: "精神分裂におけるNd,MMNのscalp current density mappingの検討" 脳波と筋電図. 25. 195-195 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 越田一郎, 伊藤憲治, 平松謙一, 福田正人, 他: "他チャンネルEEG測定装置による2次元トポグラフィ処理の評価" 脳波と筋電図. 25. 132-132 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 福田正人, 畑哲信, 丹羽真一, 伊藤憲治, 他: "精神分裂病の思考障害" 電子情報通信学会技術研究報告. TL97-7. 17-29 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Mazuka R, Itoh K, Kondo T: "Processing down the garden path in Japanese : processing of sentences with lexical homonyms." Journal of Psycholinguistic Research. 26. 207-228 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 丹羽真一, 鶴紀子, 伊藤憲治, 他: "事象関連電位・事象関連電位と情報科学の発展" 新興医学出版, 205 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 伊藤憲治,越田一郎,平松謙一,他: "思考支援・評価のための脳機能情報呈示システム" 電子情報通信学会1996年基礎・境界ソサイエティ大会講演論文集. S1. 324-325 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 平松謙一,福田正人,伊藤憲治,他: "選択的注意課題を用いた注意関連磁場とミスマッチ磁場の検討" 脳波と筋電図. 24. 131-131 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 中込和幸,福田正人,伊藤憲治,他: "Nd,MMNのScalp current density mappingの検討" 脳波と筋電図. 24. 131-131 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 中込和幸,福田正人,伊藤憲治,他: "精神分裂病におけるNd,MMNのscalp current density mappingの検討" 第26回日本脳波・筋電図学会学術大会予稿集. 326-326 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 越田一郎,伊藤憲治,平松謙一,他: "多チャンネルEEGトポグラフィシステムによるトポグラフィ補完法の評価" 脳波と筋電図. 24. 120-120 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Yokoyama H,Niwa S,Itoh K,et al: "Fractal property of eye movements in schizophrenia" Biological Cybernetics. 75. 137-140 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 鶴紀子,丹羽真一,伊藤憲治,他: "事象関連電位と神経情報科学の発展" 新興医学出版(印刷中), (1997)

    • Related Report
      1996 Annual Research Report

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Published: 1996-04-01   Modified: 2016-04-21  

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