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Investigation into Etiology of Idiopathic Scoliosis

Research Project

Project/Area Number 08650105
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Materials/Mechanics of materials
Research InstitutionTOYOHASHI UNIVERSITY OF TECHNOLOGY

Principal Investigator

AZEGAMI Hideyuki  TOYOHASHI UNIVERSITY OF TECHNOLOGY,Faculty of Engineering, Associate Professor, 工学部, 助教授 (70175876)

Project Period (FY) 1996 – 1997
Project Status Completed (Fiscal Year 1997)
Budget Amount *help
¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 1997: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1996: ¥1,200,000 (Direct Cost: ¥1,200,000)
KeywordsScoliosis / Idiopathic Scoliosis / Thoracic Type / Growth / Buckling / Numerical Analysis / Finite Element Method / 脊柱側弯症 / 特発性側弯症
Research Abstract

Since the appearance of idiopathic scoliosis is characterized by deformation of the spine, etiological research into mechanical aspects can help to establish the foundations for investigation of physiological causes and development of suitable treatments. The objective of this study was to make clear the mechanical etiology of thoracic idiopathic scoliosis, focusing on the hypothesis of a buckling mechanism generated by an imbalance in the growth speeds between the vertebrae and the surrounding structures as advocated by Shinoda et al.and Dickson et al.A finite element model of the spine together with the thoracic cage was maid to analysis growth deformation in the T4 to T10 vertebrae. The results yielded deformation that reduced thoracic kyphosis similar to what is observed in healthy children in early adolescence. In the process of increasing this deformation, the first to the fourth buckling modes were obtained, corresponding to the first bending mode in the coronal plane, the first rotation mode, the first bending mode in the sagittal plane, and the second bending mode in the coronal plane. The shape of the fourth mode agreed well with the clinical shapes. Considering the effect of posture on controlling the generation of these first bending and rotation modes and the absence of major muscles to correct the second bending mode, we presented a hypothesis that the 2nd bending mode in the coronal plane is one of the most likely etiological candidates in the mechanics of thoracic idiopathic scoliosis. To evaluate the growth rate and the shape of the fourth buckling mode precisely, nonlinear analysis using a more refined finite element model and experiment with a mechanical model were attemped. In the term of the research project, we made the finite element model and done a preliminary experiment. Sufficient results will be obtained in the future work.

Report

(3 results)
  • 1997 Annual Research Report   Final Research Report Summary
  • 1996 Annual Research Report
  • Research Products

    (11 results)

All Other

All Publications (11 results)

  • [Publications] 畔上 秀幸, 他7名: "特発性側彎症の成因に関する数値シミュレーション" 脊柱変形. 10・1. 16-19 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 畔上 秀幸, 他5名: "特発性側彎症の成因に関する数値シミュレーション-胸廓モデルを用いた検討-" 脊柱変形. 11・1. 9-12 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] H.Azegami, 他5名: "Numerical Simulation on the Etiology of Idiopathic Scoliosis" Proceedings of the Tenth International Conferences on Mechanics in Medicine and Biology. 229-232 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] H.Azegami, et al.: "Numerical Simulation on Etiology of Idiopathic Scoliosis" Spinal Deformity, The Journal of Japanese Scoliosis Society. Vol.10 No.1. 16-19 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] H.Azegami, et al.: "Numerical Simulation on Etiology of Idiopathic Scoliosis -Using a Thoracic Cage Model-" Spinal Deformity, The Journal of Japanese Scoliosis Society. Vol.11 No.1. 9-12 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] H.Azegami, et al.: "Numerical Simulation on the Etiology of Idiopathic Scoliosis" Proceedings of the Tenth International Conferences on Mechanics in Medicine and Biology. 229-232 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 畔上秀幸,他7名: "特発性側弯症の成因に関する数値シミュレーション" 脊柱変形. 10.1. 16-19 (1995)

    • Related Report
      1997 Annual Research Report
  • [Publications] 畔上秀幸,他5名: "特発性側弯症の成因に関する数値シミュレーション-胸廓モデルを用いた検討-" 脊柱変形. 11.1. 9-12 (1996)

    • Related Report
      1997 Annual Research Report
  • [Publications] H.Azegami, 他5名: "Numerical Simulation on the Etiology of Idiopathic Scoliosis" Proceedings of the Tenth International Conferences on Mechanics in Medicine and Biology. (発表予定). (1998)

    • Related Report
      1997 Annual Research Report
  • [Publications] 畔上秀幸,他7名: "特発性側彎症の成因に関する数値シミュレーション" 脊柱変形. 10巻1号. 16-19 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] 畔上秀幸,他5名: "特発性側彎症の成因に関する数値シミュレーション-胸廓モデルを用いた検討-" 脊柱変形. 11巻1号. 9-12 (1996)

    • Related Report
      1996 Annual Research Report

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Published: 1996-04-01   Modified: 2016-04-21  

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