| Project/Area Number |
08650473
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
計測・制御工学
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| Research Institution | Tohoku University |
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Principal Investigator |
KANAI Hiroshi Tohoku University, School of Engineering, Assoc.Professor, 大学院・工学研究科, 助教授 (10185895)
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| Co-Investigator(Kenkyū-buntansha) |
KOIWA Yoshiro Tohoku University, School of Medicine, Assoc.Professor, 医学部, 助教授 (80091685)
CHUBACHI Noriyoshi Tohoku Gakuin University, Faculty of Engineering, Professor, 工学部, 教授 (20006224)
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| Project Period (FY) |
1996 – 1997
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| Project Status |
Completed (Fiscal Year 1997)
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| Budget Amount *help |
¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 1997: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1996: ¥1,900,000 (Direct Cost: ¥1,900,000)
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| Keywords | myocardial elastic characteristics / cardiomyopathy / spectrum analysis / ultrasonic diagnosis / non-invasive diagnosis / ultrasonic Doppler method / small vibration measurements / diseases of circulatory system |
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| Research Abstract |
For the noninvasive diagnosis of heart disease based on the acoustic characteristics of the heart muscle, we have developed a new method for accurately tracking the movement of the heart wall. By this method, a velocity signal of the heart wall with a small amplitude of less than 10 mum on the motion resulting from a heartbeat with large amplitude of 10 mm can be successfully detected with sufficient reproducibility in the frequency range up to several hundred Hertz continuously for periods of about ten heartbeats.
In this research, the method is applied to multiple points preset in the left ventricular (LV) wall along the ultrasonic beam so that the spatial (depth) distributions of the velocity at these points are simultaneously obtained. The motion of the heart wall is divided into the following two components : parallel global motion of the heart wall and the change in myocardial layr thickening at each depth across the LV wall during myocardial contraction/relaxation. The latter component is superimposed on the M (motion) -mode image using a color code to map contraction as red and expansion as blue. By preliminary human studies, the principle of the method proposed in this paper is verified and the frequency band of the components generated by thickening and/or thinning in the myocardium is identified. This new approach offers potential for research on noninvasive acoustical diagnosis of myocardial local motility, that is, the myocardial layr function at each depth in the ventricular wall.
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