| Project/Area Number |
08670455
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Keio University |
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Principal Investigator |
KAMAKURA Mitsuhiro School of Medicine, Keio University, Assistant Professor, 医学部, 専任講師 (60169604)
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| Co-Investigator(Kenkyū-buntansha) |
SHIMADA Naoki School of Medicine, Keio University, Assistant Professor, 医学部, 専任講師 (90255430)
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| Project Period (FY) |
1996 – 1997
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| Project Status |
Completed (Fiscal Year 1997)
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| Budget Amount *help |
¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 1997: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1996: ¥1,200,000 (Direct Cost: ¥1,200,000)
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| Keywords | AIDS / HIV / tuberculosis / epidemiology / surveillance system / network system |
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| Research Abstract |
It is estimated that approximately 8.7 million people in the world have both HIV and TB infection. About 60 percent cases are esimated to have occurred in sub-Saharan Africa, and 30% in Southeast Asia. Prevention of outbreaks of Multi-drug-resistant TB and nosocomical epidemic of active TB among HIV infected patients are clinically very important. The increase of TB cases and other advanced diseases with the epidemic of HIV infection has brought about the rise of medical expenses in many countries. Administration of preventive treatment of TB for HIV carriers are important as preventive measures in both developed and developing countries in the world. Discrepancies between reported case rates and incidence estimates of tuberculosis should be taken into consideration, but in the African Region, for example, case notifications have increased steadily that reflects improved case-finding as well as the impact of the HIV epidemic. In 1995 nearly three million people in the world died from TB disease and today the global tuberculosis epidemic is more spreading than in any other year in history. An estimated 90 million people will become sick with TB in the next ten years. Multi-drug-resistant TB raises the even more alarming prospect that TB may become incurable. Outbreaks of Multi-drug-resistant TB and nosocomical epidemic of active TB among HIV infected patients are clinically very serious problem. The increase of TB cases and other advanced diseases with the epidemic of HIV infection has brought about the rise of medical expenses in many countries. Administration of preventive treatment of TB for HIV carriers in developing countries and accurate diagnosis of bacteria negative pulmonary and extrapalmonary TB disease are important as preventive measures in the world.
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