| Project/Area Number |
08670865
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Pediatrics
|
|---|
| Research Institution | Fukui medical university, faculty of medicine |
|---|
Principal Investigator |
HIRAOKA Masahiro Fukui Medical University, Faculty of Medicine, Instructor, 医学部, 助手 (20158512)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
堀 親秀 福井医科大学, 医学部・附属病院, 助手 (50242607)
|
|---|
| Project Period (FY) |
1996 – 1998
|
| Project Status |
Completed (Fiscal Year 1998)
|
| Budget Amount *help |
¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 1998: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1997: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1996: ¥1,100,000 (Direct Cost: ¥1,100,000)
|
|---|
| Keywords | Ultrasound screening / Vesicoureteral reflux / Reflux nephropathy / Renal hypoplasia / Obstructive uropathy / Renal failure / 水腎症 / 腎尿路奇形 / 超音波スクリーニング / 膀胱機能検査 / 膀胱尿管逆流 / 先天性腎尿路異常 / 尿路のスクリーニング |
|---|
| Research Abstract |
The present study on ultrasound screening for urinary tract anomalies in a large number of apparently healthy neonates revealed that hypoplastic kidneys were highly associated with ureteric reflux and that significant ureteric reflux presented with transient pelvic dilation on voiding. The present study effectively identified vesicoureteral reflux in approximately 1% of babies and observed that male babies had ureteric reflux approximately two times as often as females and that renal hypoplasia with reflux was found with an incidence of 1 in 300 boys. These findings strongly suggest that small kidneys often found in male infants who developed urinary infection were almost always associated with congenital hypoplastic kidneys. Recent investigation observed that most of children who required renal replacement therapy had had severe obstructive nephropathy or hypodysplastic kidneys. These severe renal malformations seem efficiently found in fetal ultrasound which is routinely performed by obstetrician. It seems most cost-effective to examine only these babies after birth who are suspected of having renal anomalies on fetal ultrasound.
|
