| Project/Area Number |
08670993
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Hokkaido University |
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Principal Investigator |
YOSHIKAWA Hiroyuki Hokkaido Univ, Medical Hospital., Instructor, 医学部・附属病院, 助手 (50158416)
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| Co-Investigator(Kenkyū-buntansha) |
NANNBU Toshikazu Hokkaido Univ, Medical Hospital., Instructor, 医学部・附属病院, 助手 (20261307)
FUJITA Nobuyuki Hokkaido Univ, Medical Hospital., Associate Professor, 医学部・附属病院, 助教授 (60113619)
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| Project Period (FY) |
1996 – 1997
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| Project Status |
Completed (Fiscal Year 1997)
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| Budget Amount *help |
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1997: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1996: ¥1,400,000 (Direct Cost: ¥1,400,000)
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| Keywords | osteoporosis / MRI / T2^* / T2^★ / 骨粗髪症 |
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| Research Abstract |
Osteoporosis is characterized by demineralization of bone matrix, and T2^* will be prolonged due to diminution of susceptibility. The purpose of this study is to evaluate osteoporosis with MR imagint. MR images of the lumbar spine were obtained with gradient echo sequence. TR was 500 msec, and TEs were 4.5,9.3,14.1 (in phase), 6.9,11.7, and 16.5 msec (out of phase). Group A was consisted with 13 patients administered steroids for collagen disease, and group B was composed with 11 patients without steroids. T2^* was calculated from the decline of signal intensity - TE line. Mean T2^* values of patients with and without steroid therapy were 0.014 and 0.013, respectively, and there was no significant difference between these two groups. Bone matrix could not be evaluated with these methods.
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