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Investigations for Improving Detectability of Intracranial Aneurysms using MR Angiography-Intracranial Aneurysm Model Study-

Research Project

Project/Area Number 08671017
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionHamamatsu University School of Medicine

Principal Investigator

ISODA Haruo  Hamamatsu University School of Medicine, Department of Radiology, Clinical Instructor, 医学部附属病院, 助手 (40223060)

Co-Investigator(Kenkyū-buntansha) TAKEHARA Yasuo  Hamamatsu University School of Medicine, Department of Radiology, Assistant Prof, 医学部附属病院, 講師 (70188217)
TAKAHASHI Motoichiro  Hamamatsu University School of Medicine, Department of Radiology, Associate Prof, 医学部附属病院, 助教授 (20115489)
Project Period (FY) 1996 – 1997
Project Status Completed (Fiscal Year 1997)
Budget Amount *help
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1997: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1996: ¥900,000 (Direct Cost: ¥900,000)
Keywordsintracranial aneurysm / MR angiography / MR tagging / contrast medium / phantom study / pulsatile flow / intractaniol aneurysm
Research Abstract

We investigated the flow in lateral saccular and terminal saccular intracranial aneurysm models with different sizes of necks, using tagged MR imaging. We studied 2 lateral and 2 terminal saccular aneurysm models with pulsatile flow. Their height and fundus diameter were 10 mm and their neck diameters were 2.5 mm, 10 mm respectively. Imaging was performed using a 1.5 T superconducting MR system. Tag stripes in the lateral saccular aneurysm models rotated like waterwheels rotate in a stream. A tag stripe in the lateral saccular aneurysm model with a neck size of 10 mm rotated faster than in the aneurysm model with a neck size of 2.5 mm. Although a tag stripe in the terminal saccular aneurysm model with a neck size of 2.5 mm rotated slowly, no distinct tag stripe in the model with a neck size of 10 mm was recognized probably due to very fast flow in the aneurysm model.
We also investigated the signal intensity in these aneurysm models using three dimensional (3D) time-of-flight (TOF) MR angiography with various imaging parameters. Non-contrast 3D TOF MR angiography proved able to delineate terminal saccular aneurysms and/or aneurysms with wider necks, and unable to delineate lateral saccular aneurysms and/or aneurysms with narrower necks. Longer TR or contrast-enhanced MR angiography is recommended in order to allow the spins flowing into the aneurysms to recover.
We compared enhanced 3D MR angiography using ultra fast SPGR with 2D and 3D TOF MR angiography for visualization of the intracranial lateral saccular aneurysm model. Contrast enhanced multiphase 3D MR angiography using ultra fast SPGR with shorter TR and TE more clearly demonstrated the lateral saccular aneurysm model than the other MR angiographic techniques. Contrast enhanced 3D MR angiography was thought to be promising MR angiographic technique for visualizing the intracranial aneurysm.

Report

(3 results)
  • 1997 Annual Research Report   Final Research Report Summary
  • 1996 Annual Research Report
  • Research Products

    (4 results)

All Other

All Publications (4 results)

  • [Publications] 礒田 治夫: "脳動脈瘤モデルを用いた磁気共鳴血管撮影による脳動脈瘤抽出向上に関する研究-MR teygingによる脳動脈瘤内血行動態の解析とMR angiogeaphyによる脳動脈瘤抽出能の検討" INNERVISION. 12. 23- (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Haruo Isoda: "MR Anyiography of Aneurysm Modols of Various Shapes and Nack Sizes" Am J Neuroradiol. 18. 1463-1472 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Haruo Isoda, Yasuo Takehara, Motoichiro Takahashi, Masao Kaneko, Yasuomi Kinosada, Tatsuhiko Ito: "Investigations for Improving Detectability of Intracranial Aneurysms using MR Angiography-Study of Intracranial Aneurysm flow using MR Tagging and Intracranial Aneurysm Detection using MR Angiography-." INNERVISION. 12. 23 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Haruo Isoda, Ruth G Ramsey, Yasuo Takehara, Motoichiro Takahashi, Masao Kaneko: "MR Angiography of Aneurysm Models of Various Shapes and Neck Size." AJNR Am J Neuroradiol. 18. 1463-1472 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary

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Published: 1996-04-01   Modified: 2016-04-21  

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