| Project/Area Number |
08671478
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | Iwate Medical University, School of Medicine |
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Principal Investigator |
SAITO Kazuyoshi Iwate Medical University, Department of Surgery I,Professor, 医学部, 教授 (90048348)
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| Co-Investigator(Kenkyū-buntansha) |
SHIMADA Yutaka Iwate Medical University, Department of Surgery I,Assistant, 医学部, 助手 (40285630)
中館 興一 岩手医科大学, 教養部, 教授 (40048260)
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| Project Period (FY) |
1996 – 1997
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| Project Status |
Completed (Fiscal Year 1997)
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| Budget Amount *help |
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1997: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1996: ¥1,800,000 (Direct Cost: ¥1,800,000)
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| Keywords | black gallstone / calciumbilirubinate stone / calcium carbonate stone / aragonite / calcite / hydroxyapatite / whitlockite / calcite / ビリルビンマルシウム胆石 / X線回折法 / vaterite / 炭酸カルシウム結晶 |
|---|
| Research Abstract |
Chemical and crystallographic analysis, by powder X-ray diffractometry, were carried out on black-and calcium bilirubinate gallstones.
Hydroxyapatite and whitlockite [TCP] were identified in black qallstones. HAP was found in twenty gallstones speciments, TCP in eight, but the remaining six specimens contained HAP plus TCP.
There was a close correlation between the calcium contents and phosphorus contents of both HAP,the following correlation was found : Y=2.154X+18.00, r=0.9943. For the specimens containing TCP,Y=1.964X+13.43, r=0.9994. The slope of each regression line was nearly equal to the idealized Ca/P weight ratio of 2.157 (HAP) or 1.941 (TCP).
Crystallographic pattern of calcium carbonate in calcium carbonate pius calcium phosphate stone group, calcite was dominant, but in calcium carbonate group aragonite was dominant.
On X-ray diffractometry, some peak similar with that of calcium bilirubinate stones was found at low angle area.
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