| Project/Area Number |
08671938
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Obstetrics and gynecology
|
|---|
| Research Institution | NIPPON MEDICAL SCHOOL |
|---|
Principal Investigator |
YONEYAMA Yoshio NIPPON MEDICAL SCHOOL OBSTETRICS AND GYNECOLOGY ASSISTANT PROFESSOR, 医学部, 講師 (00201096)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
石川 みずえ 日本医科大学, 医学部, 助手
|
|---|
| Project Period (FY) |
1996 – 1998
|
| Project Status |
Completed (Fiscal Year 1998)
|
| Budget Amount *help |
¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 1998: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1997: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1996: ¥1,100,000 (Direct Cost: ¥1,100,000)
|
|---|
| Keywords | adenosine / preeclampsia / platelet aggregation / 胎児 / 代謝 |
|---|
| Research Abstract |
[PURPOSE]
The purpose of this study is to evaluate the relationship between the inhibitory effect of adenosine on platelet function in pregnancies complicated by preeclampsia.
[METHOD]
We mesured plasma adenosine cconcentration in normal and preeclamptic women, then evaluate the relationship between plasma adenosine concentration and platelet function.
[RESULTS]
Maternal plasma adenosine concentration in preeclamptic women was significantly higher than the respective values in normal pregnant women, and which was associated with inhibitory effect of platelet aggregation.
[CONCLUSION]
This study has suggested that plasma adenosine may play role in regulation of platelet function in pregnancies complicated by preeclampsia.
|
