| Project/Area Number |
08672241
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
補綴理工系歯学
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| Research Institution | HIROSHIMA UNIVERSITY |
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Principal Investigator |
TAMAMOTO Mitsuhiro Hiroshima University, Dental Hospital, Assistant Professor, 歯学部・附属病院, 講師 (00136110)
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| Co-Investigator(Kenkyū-buntansha) |
NISHIMURA Masahiro Hiroshima University, School of Dentistry, Research Associate, 歯学部, 助手 (00294570)
ISHII Toshiya Hiroshima University, School of Dentistry, Research Associate, 歯学部, 助手 (70294569)
ABEKURA Hitoshi Hiroshima University, School of Dentistry, Research Associate, 歯学部, 助手 (30159454)
SADAMORI Shinsuke Hiroshima University, Dental Hospital, Assiatant Professor, 歯学部・附属病院, 講師 (40187167)
岩永 博行 広島大学, 歯学部・附属病院, 助手 (00263723)
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| Project Period (FY) |
1996 – 1997
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| Project Status |
Completed (Fiscal Year 1997)
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| Budget Amount *help |
¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 1997: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1996: ¥1,500,000 (Direct Cost: ¥1,500,000)
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| Keywords | sapacer / osteoradionecrosis / interstitial brachytherapy / tongue cancer |
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| Research Abstract |
For the purpose of preventing osteonecrosis following interstitial brachytherapy for tongue cancer, a spacer has been prepared with the intention of reducing bone dose by keeping the mandible at a distance from source. Previous reports have described the use of spacers made from several materials, including cotton rolls, gauze, impression modeling plastic, and elastic impression materials ; however, each of the materials has disadvantages. These spacers are not easy to make, place accurately and remove, and stable and comfortable for the patients. This study investigated to develope new types of acrylic resin spacers with marked reducing ability on radiation does to be easily to make, place accurately and remove, and stable and comfortable for the patiants. The results of this were as follows.
(1) It was shown that both an acylic resin and a silicone impression material of over 10 mm thickness made it possible to obtain a marked dose reduction effect.
(2) Tree types of spacers, a mouth guard-type spacer for dentate patients, a replica denture-type spacer for edenturous patients and a replica biterim-type spacer for edenturous patients without denture and dentate patients without enough making time for spacers, were developed.
(3) These tree types of spacers were comfortable for patients and prevented osteoradionecrosis of the mandible following interstitial brachytherapy for tongue cancer.
(4) According to the results through questionnaires sent to medical facilities, 91.4% of these medical facilities used several types of spacers. It was suggested that these spacers prevented osteoradionecrosis of the mandible following interstitial brachytherapy for tongue cancer.
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