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Biomechanical Study on Reconstruced Mandible by Distraction Osteogenesis

Research Project

Project/Area Number 08672298
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Surgical dentistry
Research InstitutionNagoya University (School of Medicne)

Principal Investigator

SAWAKI Yoshihiro  Nagoya University School of Medicine, Assistant Proffesor, 医学部, 講師 (00215906)

Co-Investigator(Kenkyū-buntansha) HAGINO Hiroko  Nagoya University School of Medicine, Senior Resident, 医学部, 医員
ODA Tomoo  Nagoya University School of Medicine, Senior Resident, 医学部, 医員
HATA Ken-ichiro  Nagoya University School of Medicine, Assistant Proffesor, 医学部, 助手 (80293710)
KASUYA Masayo  Nagoya University School of Medicine, Assistant Proffesor, 医学部, 助手 (20109325)
大久保 肇  名古屋大学, 医学部, 医員
山本 浩貴  名古屋大学, 医学部, 医員
野阪 泰弘  名古屋大学, 医学部, 助手 (10273236)
Project Period (FY) 1996 – 1997
Project Status Completed (Fiscal Year 1997)
Budget Amount *help
¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 1997: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1996: ¥1,300,000 (Direct Cost: ¥1,300,000)
Keywordsdistraction osteogenesis / mandibular reconstruction / osseointegrated implant / intraoral device / radiologic evaluation / histological observation / 骨結合型インブラント / X線学的観察 / 組織学的観察 / 下顎骨 / 骨結合型人工歯根 / 口内式仮骨延長装置 / 再建 / 力学的解析
Research Abstract

This study was designed to evaluate the possibility of distraction osteogenesis in bridging segmental mandibular defectusing osseointegrated implants and an intraoral device. Ten adult dogs served as the subjects of this experiment. Their left mandibular premolars and first molar were extracted. Afetr 3 months for healing, three 10 mm x 3.75 mm osseointegrated implants were installed. Following 3 months for osseointegration, abutments and intraoral device which was originally made were connected to fixtuers. The mandible was resected and fixed with reconstruction plate. An osteotomy created a transport segment of 10 mm of the mandible. Each defect was vreated by cutting out a 15 mm. Wainting for a week as the latency period, distraction of transport segment was began at a rate of 1 mm/day. After distraction was completed, the distaction device was left for 8 weeks as the consolidation period. As the result, mandibular defecsts were filled with new formed bone. No mobility of the implants was observed during and after distraction. The gingiva which covered the defect was pushed out, and the gingiva over the regenerated bone were lengthened by distraction. Radiographic evaluation demonstrated new bone formation in the distraction gap and no bone resorption around the implants.

Report

(3 results)
  • 1997 Annual Research Report   Final Research Report Summary
  • 1996 Annual Research Report
  • Research Products

    (19 results)

All Other

All Publications (19 results)

  • [Publications] Oda T., Sawaki Y., et al: "Segmental mendibular reconstruction by distraction osteogenesis under skin flaps" International Journal of Oral and Maxillofacial Surgery. 27(1). 9-13 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 澤木 佳弘 萩野 浩子 他: "仮骨延長訂に存在する歯胚の経過に関する実験的研究" 日本口腔科学会雑誌. 47(1). 39-43 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Sawaki Y., Hagino H., etal: "Trifocal distraction osteogenesis for segmental mandibular defect:A technical innovation" Journal of Cranio-Maxillofacial Surgery. 25(6). 310-315 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Yamamoto H., Sawaki Y., etal: "Maxillory advancement by distraction osteogenesis using osseolnfegrated implants" Journal of Cranio-Maxillofacial Surgery. 25(2). 186-191 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] 澤木 佳弘 萩野 浩子 他: "下顎骨区域欠損を仮骨延長法により再建した例" 日本口腔外科学会雑誌. 43(4). 564-566 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Oda, T., Sawaki, Y., Ohkubo H., Ueda M., Fukuta K.: "Segmental mandibular reconstruction by distraction osteogenesis under skin flaps." Int J Oral Maxillofac Surg. 27. 9-13 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Sawaki Y., Hagino H., Oda T., Mizutani H., Ueda M.: "Experimental study on the toothbud in area of distraction osteogenesis" J Jpn Stomatol Soc. 47. 39-43 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Sawaki H., Hagino H., Yamamoto H., Ueda M.: "Trifocal distraction osteogenesis for segmental mandibular defect : a technical innovation." J Cranio-Maxillofac Surg. 25. 310-315 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Yamaoto H., Sawaki Y., Ohkubo H., Ueda M.: "Maxillary advancement by distraction osteogenesis using osseointegrated implants." J Cranio-Maxillofac Surg. 25. 186-191 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Sawaki Y., Hagino H., Yamamoto H., Shigetomi T., Mizutani H., Ueda M.: "Distraction osteogenesis for a segmental bone defect in the mandible : Report a case." Jpn J Oral Maxillofac Surg. 43. 546-566 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1997 Final Research Report Summary
  • [Publications] Oda T., Sawaki Y., et al.: "Segmental mendibular reconstruction by distraction Osteogenesis under skin flaps" Intermational Journal of Orcl and Maxillofacial Surgery. 27(1). 9-13 (1998)

    • Related Report
      1997 Annual Research Report
  • [Publications] 澤木佳弘 荻野浩子 他: "仮骨延長部に存在する歯胚の経過に関する実験的研究" 日本口腔科学会雑誌. 47(1). 39-43 (1998)

    • Related Report
      1997 Annual Research Report
  • [Publications] Sawaki Y., Hagino H., et al.: "Trifocol distraelion osteogemesis for segmental mandibular defect:A technical immovation." Journal of Cramio-Maxillofacial Surgery. 25(6). 310-315 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Yamamoto H., Sawaki Y., et al.: "Maxillory advancemont by distraction OSteogenesis using Osseolntegrhtad implants." Journal of Cranio-Maxillofacial Surgery. 25(2). 186-191 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 澤木佳弘,荻野浩子 他: "下顎骨区域欠損を仮骨延長法により再建した1例" 日本口腔外科学会雑誌. 43(4). 564-566 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Y.SAWAKI et.al.: "Mandibular Lengthening by Distraction Osteogenesis Using Osseointegrated Implants and Intraoral Device : A Preliminary Report" Journal of Oral Maxillofacial Surgery.

    • Related Report
      1996 Annual Research Report
  • [Publications] Y.SAWAKI et.al.: "Mandibular Lengthening by Intraoral Distraction Using Osseointegrated Implants" The International Journal of Oral and Maxillofacial Implants.

    • Related Report
      1996 Annual Research Report
  • [Publications] T.Oda et.al.: "Segmental Mandibular Reconstraction Distraction Osteogenesis under Skin Flap" International Journal of Oral and Maxillofacial Surgery. (accepted). (1997)

    • Related Report
      1996 Annual Research Report
  • [Publications] H.OHKUBO et.al.: "Experiment Study of Distraction by Osteogenesis in Maxillofacial Region" Journal of Craniofacial Surgery. (accepted). (1997)

    • Related Report
      1996 Annual Research Report

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Published: 1996-04-01   Modified: 2016-04-21  

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