| Project/Area Number |
08672337
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | TOKYO DENTAL COLLEGE |
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Principal Investigator |
SUGIYAMA Ayako TOKYO DENTAL COLLEGE,DEPARTMENT OF DENTISTRY,LECTURER, 歯学部, 講師 (80171180)
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| Co-Investigator(Kenkyū-buntansha) |
KANEKO Yuzuru TOKYO DENTAL COLLEGE,DEPARTMENT OF DENTISTRY,PROFESSOR, 歯学部, 教授 (00085747)
ICHINOHE Tatsuya TOKYO DENTAL COLLEGE,DEPARTMENT OF DENTISTRY,ASSISTANT PROFESSOR PROFESSOR, 歯学部, 助教授 (40184626)
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| Project Period (FY) |
1996 – 1997
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| Project Status |
Completed (Fiscal Year 1997)
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| Budget Amount *help |
¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 1997: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1996: ¥800,000 (Direct Cost: ¥800,000)
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| Keywords | Electrocardiographic abnormalities / Iong poerations / Holter electrocardiography |
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| Research Abstract |
The purpose of the present study was to clarify the causes of the electrocardiographic abnormalities which occurred during and after surgery in long operations. Oral surgical patients who underwent cancer resection and gave informed consent participated in this study. Electrocardiographic abnormalities were detected by comparing electrocardiograms recorded before and on the day of surgery using Holter electrocardiograpyh (24 hrs electrocardiography). The electrocardiogram at rest recorded as a preperative examination was referred as needed. General anesthesia was induced by a rapid sequence technique and endotracheal intubation was perfomed. General anesthesia was mainatained using inhaled anesthetics with or without a intravenous analgesic. Hypoxia and hypercapnia which might provoke arrhythmias were eliminated using a blood gas analysis. Moreover, transcutaneous arterial oxygen saturation and endtidal carbon dioxide concentration were continuously monitored. The Holter electrocardiog
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ram on the day of surgery was classified into four categories and analyed ; 1) before operation, 2) from the start of operation to tumor resection, 3) from tumor resection to the end of operation, 4) after operation. Although there were no abnormalities in the electrocardiogram at rest in each patient, several types of arrhythmias were observed in the Holter electrocardiogram in many patients before surgery. However, possible cardiac disease was denied because of the severity of the arrhythmias and/or patient's subjective symptoms. The Holter electrocardiogram after surgery showed an increase in the frequency of arrhythmias shich was observed before surgery. Arrhythmias during surgery were not fully analyzed because of electric cauterization equipment. These arrhythmias did not need any treatment. Myocardial damage due to these arrhythmias was not observed.
Electrocardiographic abnormalities were provoked by cardiovascular diseases, surgical intervention, general anesthetics and/or inappropriate systemic management. Since the arrhythmias mainly occurred after surgery, general anesthetics might be excludec from the primary cause. More cases should be included and analyzed in the future study. Less
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