| Project/Area Number |
08680070
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
家政学
|
|---|
| Research Institution | NAKAMURA GAKUEN JUNIOR COLLEGE |
|---|
Principal Investigator |
MATSUGUMA Miki NAKAMURA GAKUENN JUNIOR COLLEGE,ASSISTANT, 食物栄養科, 助手 (40259669)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
FUJITA Mamoru NAKAMURA GAKUENN UNIVERSITY,PROFESSOR, 家政学部, 教授 (60037471)
馬場 良子 中村学園大学, 家政学部, 助手 (90271436)
|
|---|
| Project Period (FY) |
1996 – 1997
|
| Project Status |
Completed (Fiscal Year 1997)
|
| Budget Amount *help |
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1997: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1996: ¥700,000 (Direct Cost: ¥700,000)
|
|---|
| Keywords | FOOD ALLERGY / FOOD ANTIGEN / SMALL INTESTINE / HISOCHEMISTRY / UL TRANSTRUCTURE / MACROMOLECULE / 植物性レクチン / 乳飲期ラット / 小腸 / 空腸 |
|---|
| Research Abstract |
Suckling animals are able to absorb meternal immunoglubulins from milk in the jejunal epithelial cells and to transport these proteins intact to the circulation. Wearing and adult animals, however, don't absorb macromolecules in the jejunal and ileal epitelial cells. To determine whether an inversion of food antigens at the initial stages of allergy occurred with absorption of maternal antibody, tracer, histochemistry, cytochemistry and ultrastructural studies were used in the small intestine of the suckling rats.
These results were suggested that food antigen and macromolecules invaded in connection with mechanism which maternal antibody transport across the jejunal absorptive cells in suckling rats.
|
