Role of ob product on weight reduction through exercises or hihg carbohydrate diet in rats.

• Project/Area Number: 08680091
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: 体育学
• Research Institution: University of Tsukuba
• Principal Investigator: TAGAMI Kazumi University of Tsukuba Health & sport scis., Assoc., 体育科学系, 助教授 (40171566)
• Co-Investigator(Kenkyū-buntansha): SUZUKI Masashige University of Tsukuba Health & Sprot Scis., Prof., 体育科学系, 教授 (90015842) ; SAITOH Shinichi University of Tsukuba Health & sport Scis., Assoc.Prof., 体育科学系, 助教授 (80114081)
• Project Period (FY): 1996 – 1997
• Project Status: Completed (Fiscal Year 1997)
• Budget Amount: ¥2,200,000 (Direct Cost: ¥2,200,000); Fiscal Year 1997: ¥900,000 (Direct Cost: ¥900,000); Fiscal Year 1996: ¥1,300,000 (Direct Cost: ¥1,300,000)
• Keywords: OBESITY / OB GENE / RESISTANCE EXERCISE / LEPTIN / RATS / ENDURANCE EXERCISE / ob遺伝子

Research Abstract

Zhang et al. (1994) found ob gene and the roles of appetite reduction on the product ; leptin secreted form mature adipose cells as a hormone-like manner. Here, we recognized a new phenomenon that serum leptin was lowered by both type of exercise, endurance of resistance and lowered by high carbohydrate diet feeding. As the results, higher serum leptin made higher body weight or higher abdominal fat depot in our experimental conditions. Therefore, we thought that physiological or endogenous leption would be regulated via different manner from that of exogenously administered recombinant one.

Research Products

• [Publications] Saitoh, S. et al.: "Effects of short-term dietary change from a high fat diet to a high carbohydrate diet and with or without energy restriction on muscle and liver glycogen stores in untrained rats." Adv.Exerc.Sports Physiol.3. 75-81 (1997)
  • Description: 「研究成果報告書概要(和文)」より
• [Publications] S.SAITOHO,H.CHANG,A.MORINAGA,S.JIK LEE,K.TAGAMI,& M.SUZUKI.: "Effects of short-term dietary change from a high fat diet to a high carbohydrate diet and with or without energy restriction on muscle and liver glycogen stores in untrained rats." ADV.EXERC.SPORTS PHYSIOL.3(2). 75-81 (1997)
  • Description: 「研究成果報告書概要(欧文)」より
• [Publications] Saitoh,S.et al.: "Effects of short-term dietary change from a high fat diet to a high carbohydrate diet and with or without energy restriction on muscle and liver glycogen stores in untrained rats" Adv.Exerc.Sports Physiol.3・2. 75-81 (1997)