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Study on genetic and cultural diversity of Hans in China

Research Project

Project/Area Number 09041118
Research Category

Grant-in-Aid for international Scientific Research

Allocation TypeSingle-year Grants
SectionField Research
Research Field 人類学(含生理人類学)
Research InstitutionNational Institute of Genetics

Principal Investigator

SAITOU Naruya  National Institute of Genetics, Laboratory of Evolution of Genetics, Associate Professor, 集団遺伝研究系, 助教授 (30192587)

Co-Investigator(Kenkyū-buntansha) OMOTO Keiichi  International Research Center for Japanese Studies, Professor, 教授 (10011503)
YUASA Isao  University of Tottori, Faculty of Medical Science, lecturer, 医学部・法医学, 講師 (00093633)
UEDA Shintaroh  University of Tokyo, Graduate School of Science, Associate Professor, 大学院理学系研究科, 助教授 (20143357)
HORAI Satoshi  Graduate University for Advanced Studies, Professor, 教授 (40126157)
TOKUNAGA Katsushi  University of Tokyo, Graduate School of Medical Science, Professor, 大学院医学系研究科, 教授 (40163977)
Project Period (FY) 1997 – 1998
Project Status Completed (Fiscal Year 1998)
Budget Amount *help
¥12,200,000 (Direct Cost: ¥12,200,000)
Fiscal Year 1998: ¥5,800,000 (Direct Cost: ¥5,800,000)
Fiscal Year 1997: ¥6,400,000 (Direct Cost: ¥6,400,000)
Keywordsgenetic polymorphism / Chinese dialect / ancient DNA / surname / mtDNA / HLA / serum protein / blood group
Research Abstract

We conducted the following studies in the fiscal year 1997 : (1) Iwata did a study on dialect border of Central part of China during August-September. (2) Saitou and Ueda visited Beijing and Xian in September, and collected blood samples in the surburb of Xian. Three Chinese collaborators (Jin, Yuan, and Zhan) as well as two other researchers (Wan, Kitano, and Iwamoto) also joined that study. (3) Saitou and Yuasa visited Beijing and Chansha in November, and collected blood samples in the surburb of Chansha. (4) Horai and Tokunaga visited Beijing and Kunmin in November, and collected blood samples in the surburb of Kunmin. (5) Three Chinese collaborators visited Japan and did a collaborative studies with Japanese members at University of Tokyo and National Institute of Genetics.
In the fiscal year 1998, we conducted the following studies : (1) Saitou, Ueda, and researcher Wan visited Beijing, Anyan, and Xinan, and conducted a preliminary study to extact ancient DNA from human remains. Jin Feng also attended this study. (2) Two Chinese collaborators (Jin and Cao) visited Japan in October, and studied genetic polymorphism of red blood cell enzymes on samples stored at International Center for Japanese Studies. (3) Saitou, Omoto, Horai, Tokunaga, Yuasa, and researcher Noda visited China in January 1999, and collected blood samples near Guanzhou, Fuzhou, and Hanzhou. Jin and Cao also were involved in that study. (4) Ueda visited Beijing on the ancient DNA study.

Report

(3 results)
  • 1998 Annual Research Report   Final Research Report Summary
  • 1997 Annual Research Report
  • Research Products

    (39 results)

All Other

All Publications (39 results)

  • [Publications] Saitou N.: "Evolution of primate ABO blood group genes and their homologous genes" Molecular Biology and Evolution. 14・4. 399-411 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Kitano T.: "The phylogenetic relationship of the genus Oncorhynchus species inferred from nuclear and mitochondrial markers." Genes and Genetic Systems. 72・1. 25-34 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Omoto K.: "Genetic origins of the Japanese: A partial support for the “dual structure hypothesis"." American Journal of Physical Anthropology. 102・4. 437-446 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Blagitko N.: "Polymorphism of the HLA-DRB1 locus in Colombian, Ecuadorian, and Chilean Amerinds" Human Immunology. 54・1. 74-81 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Hmmer M.F.: "The geographic distribution of human Y chromosome variation" Genetics. 145. 787-805 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Horai S.: "Peopling of Japan inferred from mitochondrial DNA polymorphisms in East Asians." World Scientific. 54-73 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Akaba K.: "Neonatal hyperbillirub inemia and mutation of the bilirubin uridine diphosphate-glucuronosyl transferase gene: a common missense mutation among Japanese, Korean and Chinese." Biochemistry and Molecular Biology International. 46・1. 21-26 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Ogawa A.: "Diversity of HLA-B61 alleles and haplotypes in East Asians and Spanish Gypsies." Tissue Antigens. 51・4. 356-366 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Oota H.: "Molecular genetic analysis of remains of a 2,000-year-old human population in China-and its relevance for the origin of the modern Japanese population" Amer.J.Human Genet.64・1. 250-258 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Kobayashi K.: "An analysis of polymorphism for the ABO blood group genes in a Japanese population based on polymerase chain reaction." Anthropological Science. 107・2 in press. (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] 斎藤成也: "遺伝子は35億年の夢を見る-バクテリアから人間の進化まで-" 大和書房, 東京, 229 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] 寶来 聰: "DNA人類進化学" 岩波書店, 120

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Hammer M.F., Jenkins T., Bonner M.R., Spudle A.B., Wood E.T., Mitchell R.J., Novelletto A., Horai S.and Zegura S.L.: "The geographic distribution of human Y chromosome variation" Genetics. 145. 787-805 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Omoto K.and Saitou N.: "Genetic origins of the Japanese : A partial support for the "dual structure hypothesis"" American Journal of Physical Anthropology. Vol.102, No.4. 437-446 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Tokunaga K,Bannai M,Imanishi T,and Juji T.: "HLA class II alleles and haplotypes in East-Asian populations with special reference to the Ainu" The Origins and Past of Modern Humans : Towards Reconciliation, Omoto K.et al.eds.World Scientific Publishing. 74-87 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] K.Ago, I.Yuasa, O.Tsuganezawa: "Transferrin polymorphism in the Nansei Islands : Description of a new variant TF Dama and clines of allele frequencies in Japanese populations" Anthropological Science. 106(3). 209-219 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] K.Ago, I Yuasa, O.Tsuganezawa: "Distribution of group-specific component/vitamin D-binding protein alleles in Southwestern Japan and geographical clines of allele frequencies in Japanese populations" Anthropological Science. 106(4). 385-395 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Horai S.and Omoto K.: "Peopling of Japan inferred from mitochondrial DNA polymorphisms in East Asians" The origin and past of modern humans-Towards a reconciliation.K.Omoto & P.V.Tobias (eds.). World Scientific. 54-73 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Oota H., Saitou N., Matsushita T., and Ueda S.: "Molecular genetic analysis of remains of a 2,000-year-old human population in China-and its relevance for the origin of the modern Japanese population" Amer.J.Human Genet. 64 (1). 250-258 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Oota H.: "Molecular genetic analysis of remains of a 2,000-year-ole human population in China-and its relev ance for the origin of the modern Japanese population." Amer.J.Human Genet.64・1. 250-258 (1999)

    • Related Report
      1998 Annual Research Report
  • [Publications] Horai S.: "Peopling of Japan inferred from mitochondrial DNA polymorphisms in East Asians." World Scientific. 54-73 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Akaba K.: "Neonatal hyperbillirubinemia and mutation of the bilirubin uridine diphosphateglucuronosyltransferasegene : a common missense mutation among Japanese, Korean and Chinese." Biochemistry and Molecular Biology International. 46・1. 21-26 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Ogawa A.: "T : Diversity of HLA-B61 alleles and haplotypes in East Asians and Spanish Gypsies." Tissue Antigens. 51・4. 356-366 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Kobayashi K.: "An analysis of polymorphism for the ABO blood group genes in a Japanese population based on polymerase chain reaction" Anthropological Science. 107・2(in press). (1999)

    • Related Report
      1998 Annual Research Report
  • [Publications] P.V.Tobias: "World Sientific Tobias and Omoto編" The Origins and Past of Modern Humans-Towards Reconciliation, (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Saitou N.: "Evolution of primate ABO blood group genes and their homologous genes" Molecular Biology and Evolution. 14・4. 399-411 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Kitano T.: "The phylogenetic relationship of the genus Oncorhynchus species inferred from nuclear and mitochondrial markers." Genes and Genetic Systems. 72・1. 25-34 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Omoto K.: "Genetic origins of the Japanese:A partial support for the "dual structure hypothesis"." American Journal of Physical Anthropology. 102・4. 437-446 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 斉藤 成也: "遺伝子の進化とは〜ABO式血液型を中心に〜" BIO Clinica. 12・11. 830-834 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Blagitko N.: "Polymorphism of the HLA-DRB1 locus in Colombian,Ecuadorian,and Chilean Amerinds" Human Immunology. 54・1. 74-81 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Hmmer M.F.: "The geographic disribution of human Y chromosome variation" Genetics. 145. 787-805 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 寶来 聰: "ミトコンドリアDNAからみた日本人" SUT BULLETIN. 14・4. 27-30 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Sumiyama K.: "Human class III POU genes,POU3F1 and POU3F3,map to chromosome 1p34.1 and 3p14.2." Mammalian Genome. (in press).

    • Related Report
      1997 Annual Research Report
  • [Publications] Nakachi Y.: "Nucleotide compositional constraints on genomes generate alanine-glycine,and proline-rich structures in transcription factors" Mol.Biol.Evol.14・10. 1042-1049 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Kurosaki K.: "Combined polymorphism associated with a 3-bp deletion in the 5'-flanking region of a tetrametic short tandem repeat at the CYP19 locus" Jpn.J.Legal Med.51・3. 191-195 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Watanabe Y.: "No directionality of short tandem repeat evolution at the HPRT locus in catarrhine primates" Folia Primatologica. 68・6. 350-353 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 斉藤 成也: "遺伝子は35億年の夢を見る-バクテリアから人間の進化まで-" 大和書房,東京, 229 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 斉藤 成也: "環太平洋人類集団の過去と未来.福田一郎・劉剛編著,「文明と遺伝」" 勉誠社,東京, 310 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 寶来 聰: "DNA人類進化学" 岩波書店, 120 (1997)

    • Related Report
      1997 Annual Research Report

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Published: 1997-04-01   Modified: 2016-04-21  

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