Ecotoxicological study on human exposure to trace elements

• Project/Area Number: 09041171
• Research Category: Grant-in-Aid for international Scientific Research
• Allocation Type: Single-year Grants
• Section: Field Research
• Research Field: Hygiene
• Research Institution: Miyagi University of Education
• Principal Investigator: WATABABE Takao Miyagi University of Education Prof., 教育学部, 教授 (20004608)
• Co-Investigator(Kenkyū-buntansha): 曲 江武 山東医科大学, 衛生学部, 助教授 ; IKEDA Masayuki Kyoto Industrial Health Association Prof., 学術顧問 (00025579) ; INOGUCHI Naoko Miyagi University Res.Assist., 看護学部, 助手 ; NAKATSUKA Haruo Miyagi University Prof., 看護学部, 教授 (70164225) ; SHIMBO Shinichiro Kyoto Women's University Prof., 短期大学部, 教授 (60027406) ; QU Jiang-Bjn Paculty of Public Health, Associ.Shandong Medical University Prof.
• Project Period (FY): 1997
• Project Status: Completed (Fiscal Year 1997)
• Budget Amount: ¥3,100,000 (Direct Cost: ¥3,100,000); Fiscal Year 1997: ¥3,100,000 (Direct Cost: ¥3,100,000)
• Keywords: China / lead / cadmium / women / trace element / nutrition / blood / food duplicate

Research Abstract

Ecotoxicolgical study on human exposure to trace elements was carried out for nonsmoking women lived in nonpolluted area in China.
Survey at three different reigons were conducted in series in November, 1997 ; one is in Xian, the capital city of Shaanxi Province, China, the second one in Bamiao village (Village A) in Baoji County in the same province (some 200km west to Xian), and the third one in Gongzhang Village (Village B) in Changan Gounty also in the same province (some 25km south-west to Xian). The 24-hr food duplicate samples, venous blood samples, daily urine samples, drinking water, rice and wheat flower were collected from 50 nonsmoking women at each of the tree regions. They had also physical examinations including hematology and serum biochemistory tests.
Daily dietary lead intakes was 26.1ug/day for Xian women, 36.1ug/day for Village A women and 45.8ug/day for Village B,as geometric mean (GM). The counterpart values for blood were 43.4ng/ml (GM) for Xian women, 22.4ng/ml (G M) for Village A and 41.8ng/ml (GM) for Village B women. Daily dietary cadmium intake was 5.8ug/day for Xian women, 5.6ug/day for Village A women and 6.8ug/day for Village B as GM.The counterpart values of cadmium for blood were 0.19ng/ml (GM) for Xian women, 0.08ng/ml (GM) for Village A and 0.08ng/ml (GM) for Village B women.
International comparison with recently published data suggests that the exposure to lead in Xian and Village B nearby the city is higher among East Asian countries and on the other side the exposure to cadmium in Xian city and Shaanxi province is the lowest among East Asian countries.
Nutritional analyzes of the duplicate samples were conducted utilizing standard food composition tables for Chinese populations. The urban-rural comparison between the tree groups showed that women in Xian took significantly more lipid (56g/day), more calcium (410mg/day) and less magnesium (306mg/day) than both of Village A and B counterparts (28 and 27g/day lipid, 301 and 302mg/day calcium, 346 and 387mg/day magnesium), although there was no significant difference in total energy and protein intake.