| Project/Area Number |
09044250
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| Research Category |
Grant-in-Aid for international Scientific Research
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| Allocation Type | Single-year Grants |
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| Section | Joint Research |
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| Research Field |
Neuroscience in general
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| Research Institution | TOHOKU UNIVERSITY |
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Principal Investigator |
FUKUDA Hiroshi Tohoku Univ., IDAC,Professor, 加齢医学研究所, 教授 (30125645)
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| Co-Investigator(Kenkyū-buntansha) |
KINOMURA Shigeo Tohoku University, IDAC,Assistant Professor, 加齢医学研究所, 助手 (70281996)
KAWASHIMA Ryuta Tohoku University, IDAC,Senior Assistant Professor, 加齢医学研究所, 講師 (90250828)
ZILLES Karl C.& O.Vogt Brain Research Institute, Professor, C&OVog研究所, 教授
ROLAND Per Karolinska Institute, Professor, 教授
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| Project Period (FY) |
1997 – 1998
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| Project Status |
Completed (Fiscal Year 1998)
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| Budget Amount *help |
¥5,700,000 (Direct Cost: ¥5,700,000)
Fiscal Year 1998: ¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 1997: ¥3,200,000 (Direct Cost: ¥3,200,000)
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| Keywords | Computerized Brain Atlas / human brain function / image database / Anatomical Normalization / PET / MRI |
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| Research Abstract |
1. Development and Evaluation of the Computerized Brain Atlas System
We validated the anatomical precision of spatial normalization with the Elastic Transformation System which has developed by Zilles's group with our collaboration. We found that this system shows high effectiveness in spatial normalization procedure compared with other systems, indicating that it can be used not only for positorn emission tomography (PET) activation studies but for functional magnetic resonance imaging (MRI) studies.
2. Functional Brain Mapping of Cognitive and Motor Function
Roland's group and our group participated this project. We used PET to investigate functional brain areas of humans involved in many kinds of cognitive or motor tasks. The results obtained are used as contents of the brain function database which has been developing by our group.
3. Development of International Brain Anatomy Database
We and Evans's group had a meeting in Montreal, and have agreed to create comparable international brain anatomy database with Zilles's group. We have decided to correct 300 3D-brain MRI of healthy subjects for each group, and to perform inter-ethnic comparisons using spatial normalization technique develped by Evans's group. Our group already corrected 150 brain MRIs, and we have estimated standard brain anatomy of the Japanese population of different age group from this data.
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