| Project/Area Number |
09044338
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| Research Category |
Grant-in-Aid for international Scientific Research
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| Allocation Type | Single-year Grants |
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| Section | Joint Research |
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| Research Field |
Hygiene
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| Research Institution | Nihon University |
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Principal Investigator |
YAJIMA Kazuyoshi Nihon University, School of Medicine, Professor, 医学部, 教授 (40010029)
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| Co-Investigator(Kenkyū-buntansha) |
ITO Masao Tokyo University for Agriculture, Faculty of Bioindustry. Proffesor, 生産産業学部, 教授 (40059887)
IGARASHI Makoto Nihon University, Research Institute, Professor, 研究所, 教授 (30231731)
KUROKAWA Kiyoshi Tokai University. School of Medicine, Professor, 医学部, 教授 (30167390)
IWASAKI Ken-ich Nihon University, School of Medicine, Assistent, 医学部, 助手 (80287630)
MIYAMOTO Akira Nihon University, School of Medicine, Assistant Professor, 医学部, 助教授 (40150271)
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| Project Period (FY) |
1997
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| Project Status |
Completed (Fiscal Year 1997)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,900,000)
Fiscal Year 1997: ¥3,900,000 (Direct Cost: ¥3,900,000)
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| Keywords | artificial gravity / human centrifuge / International Space Station / space medicine / countermeasure in space / international collaboration / stop hematocrit increase / 6 degrees head down tilt / 宇宙循環系変化の対策 / 宇宙骨格系変化の対策 / ベッドレスト / 人間用短腕遠心機 |
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| Research Abstract |
Mars-Pathfinder has been started now and human adaptation for microgravity due to long-term space flight becomes more important. Therefore, medical countermeasures for such adaptive change in space are most urgent, and indispensable. Artificial gravity is one of the most important target to be solved urgently and collaboratively. In the coming International Space Station (ISS) , an artificial gravity experirnental module is planned to be attached. But it is only for animal and not for human. We have emphasized in all occasions to set a human centrifuge in ISS in order to estimate the actual usefulness cf centrifugation effect on human as the prevention against cardiovascular deconditioning and bone mineral loss. Dr. Nicogossian and Dr. Vernikos are well recognized us, but they say this module is only for animal.
On the other part, we have conducted the experiments using a short-arm human centrifuge to prevent the hematocrit increase caused by head down tilt bed rest for four days. This is a simulation study on the ground of proving the usefulness of centrifugation in space. 2G-1 hour Gz centrifugation was adopted every day during 4 days head down tilt for 10 healthy male subjects. We have succeeded to stop the increase of hematocrit up to 4 days of head down tilt, though Convertino et al. failed by other countermeasures using exercise or standing up on the bed for 1-2 hours, and water intake etc.
More collaborative studies are necessary even internationally to solve the problem of artificial gravity; how much, how long and how often can we give them the centrifugation in space?
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