| Project/Area Number |
09240102
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| Research Category |
Grant-in-Aid for Scientific Research on Priority Areas
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| Allocation Type | Single-year Grants |
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| Research Institution | Teikyo University of Science and Technology (1999-2000)
The University of Tokyo (1997-1998) |
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Principal Investigator |
URYU Toshiyuki Teikyo University of Science and Technology, Department of Environment Material and Material Engineering, Professor, 理工学部, 教授 (80011005)
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| Co-Investigator(Kenkyū-buntansha) |
FURUKAWA Kiyoshi Tokyo Metropolitan Institute of Gerontology, Department of Biosignal Research, Head, 室長 (10190133)
KOBAYASHI Kazukiyo Nagoya University, Department of Molecular Design and Engineering, Professor, 大学院・工学研究科, 教授 (10023483)
NISHIMURA Shin-ichiro Hokkaido University, Division of Biological Sciences, Professor, 大学院・理学研究科, 教授 (00183898)
HATANAKA Kenichi University of Tokyo, Institute of Industrial Science, Associate Professor, 生産技術研究所, 助教授 (70167584)
AKIYOSHI Kazunari Kyoto University, Department of Synthetic Chemistry and Biological Chemistry, Associate Professor, 大学院・工学研究科, 助教授 (90201285)
山形 達也 東京工業大学, 生命理工学部, 教授 (10251654)
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| Project Period (FY) |
1997 – 2000
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| Project Status |
Completed (Fiscal Year 2000)
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| Budget Amount *help |
¥38,400,000 (Direct Cost: ¥38,400,000)
Fiscal Year 2000: ¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 1999: ¥13,000,000 (Direct Cost: ¥13,000,000)
Fiscal Year 1998: ¥10,000,000 (Direct Cost: ¥10,000,000)
Fiscal Year 1997: ¥12,400,000 (Direct Cost: ¥12,400,000)
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| Keywords | Saccharide chain synthesis / Aggregate of molecules / Control of biomolecules / Control of cell functions / Saccharide chain recognition / Glycopolymer / Functional polysaccharide / Biofunctional saccharide chain / 糖質自動合成システム / 共重合型糖鎖高分子 / コレステロール置換プルラン / 抗エイズウイルス活性 / エイズ薬デリバリー / ガラクトース転移酵素 / 糖タンパク質 / 硫酸化グルコース担持ポリマー / 糖鎖自動合成法 / ポリシアロガングリオシド / 人工複合糖鎖ポリマー / 両親媒性多糖 / 抗エイズウイルス作用 / 高分子コンジュゲート医薬 / 個体発生 / 植物主体防御 / オリゴ糖 / 糖脂質 / ピロテオグリカン / 生理活性 / 薬理活性 / ドラッグデリバリーシステム |
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| Research Abstract |
(1) 7 simposiums had been held.
(2) Research results of each investigator were concluded.
(3) Research results of each group (A01 : basic research on superfine synthesis of saccharide chain ; A02 : aggregate of saccharide chain ; A03 : control of biomolecules by saccharide chain ; A04 : control of cell functions by cognitive multidimensional glyco-chain) were concluded.
(4) Results of all the researchs includins cooperative researchs were concluded to produce a booklet written in English (316 pages).
(5) Research results were published (946 original papers, 187 reviews, more than 1000 oral presentations, 121 books).
(6) The book of "Design of Glyco-Molecules and Their Biological Functions" was edited.
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