| Project/Area Number |
09304069
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (A)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
物質変換
|
|---|
| Research Institution | TOHOKU UNIVERSITY |
|---|
Principal Investigator |
YAMAMOTO Yoshinori Graduate School of Science, Tohoku University, Professor, 大学院・理学研究科, 教授 (60029519)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
SAITO Shinichi Institute for Chemical Reaction Science, Tohoku University, Research Associate, 反応化学研究所, 助手 (80283076)
VLADIMIR Ger (GERORGYAW Vl) 東北大学, 大学院・理学研究科, 助教授 (80281971)
AL.MASUM Moh 東北大学, 反応化学研究所, 助手 (50282041)
|
|---|
| Project Period (FY) |
1997 – 1999
|
| Project Status |
Completed (Fiscal Year 1999)
|
| Budget Amount *help |
¥40,500,000 (Direct Cost: ¥40,500,000)
Fiscal Year 1999: ¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 1998: ¥5,500,000 (Direct Cost: ¥5,500,000)
Fiscal Year 1997: ¥31,500,000 (Direct Cost: ¥31,500,000)
|
|---|
| Keywords | Enynes / Diynes / Alkynes / Palladium / Cycloaddition / Benzene / パラジウム触媒 / 共役エンイン / 芳香環化 / スチレン誘導体 / フェノール誘導体 / フラン誘導体 / シクロファン / ヘテロ環 / プロ求核剤 / アレン |
|---|
| Research Abstract |
Monosubstituted conjugated enynes were found to undergo [4+2] homodimerization smoothly in the presence of palladium catalyst to give 4, α-and 2,6-disubstituted styrene derivatives. Analogous cross-cycloaddition of conjugated enynes and diynes was also developed to afford a variety of polysubstituted benzenes, including phenol and aniline derivatives. Alkynes and diynes in the presence of a palladium catalyst underwent novel formal [2+2+2] sequential cyclotrimerization to afford multifunctional benzenes in one step with high degrees of regio- and chemoselectivities. Mechanism of these novel transformations was proposed.
|
