| Project/Area Number |
09470121
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Grant-in-Aid for Scientific Research |
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Principal Investigator |
ARITA Mikio (2000-2001) Nursing College, Wakayama Medical University, Professor, 教授 (40168018)
武田 眞太郎 (1997-1999) 和歌山県立医科大学看護短期大学部, 教授 (70073690)
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| Co-Investigator(Kenkyū-buntansha) |
MORIOKA Ikuharu Wakayama Medical University, Assoc. Professor, 医学部, 助教授 (70264877)
MIYASHITA Kazuhisa Wakayama Medical University, Professor, 医学部, 教授 (50124889)
TAKEDA Shintaro Nursing College, Wakayama Medical University, Professor, 教授 (70073690)
SAKAMOTO Motoko Wayo Womens' University Professer, 教授 (70049980)
GOWA Yoshimoto Osaka International University, Assistant, professor, 人間科学部, 講師 (40248050)
中井 國雄 和歌山県立医科大学看護短期大学部, 教授 (20180234)
有田 幹雄 和歌山県立医科大学, 看護短期大学部, 教授 (40168018)
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| Project Period (FY) |
1997 – 2000
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| Project Status |
Completed (Fiscal Year 2001)
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| Budget Amount *help |
¥13,000,000 (Direct Cost: ¥13,000,000)
Fiscal Year 2000: ¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 1999: ¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 1998: ¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 1997: ¥5,100,000 (Direct Cost: ¥5,100,000)
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| Keywords | Childhood / peripheral circulatory function / age-related changes / blood pressure / accelerated pletysmograpy / serum fat / food intake / exercise |
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| Research Abstract |
This study was transversally undertaken to determine the changes of peripheral circulatory function and to clarity the changes of serum conditions through the use of Japanese students.
When we analyze wave forms of accelerated plethysmography (APG) in adolescent, we have to exclude effects of increasing height resulting form growth. In this project, we evaluated the index of APG, d/a, with using the standard height-d/a curves, in order to exclude the effects of increasing height. We were, then, able to clarify the relation of d/a to variable risk factors of arthevosclerosis. Consequently, the standard height-d/a curves are useful tools for evaluating the preripheral circulatory function in adolescent, who are in growing stage, by the APG. 315 healthy children (170 girls and 145 boys), mean age, 13.6 years, in elementary, junior high and high school, were transversally studied. We performed blood pressure(BP) measurements by a sphygmomanometer and measured BMI, plasma NE, INS and LEP. Obesity was found ll subjects whose LEP were 16.6±13.3 ng/ml. INS were 16.2±7.5 μ/ml and total energy consumption were 2450±330 kcal. These were significantly higher than normal controls(p<0.001). Hypertensives were9 subjects and with body weight until 12 years. Boys always had lower LEP levels than girls. There was appositive correlation between LEP and BMI(r=0.38, p<0.001), diastolic(D)BP(r=0.14, p=0.009), INS(r=0.19, p<0.001). Stepwise logistic regression showed that MI(t=8.95), DBP(t=2.71)and INS(t=2.33)were significant correlation with LEP. These data suggest that in the children 1)obesity were found only 3.5%, whose leptin, insulin and consumption energy were extremely high and 2)leptin have a significant correlation with BMI and DBF.
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